Acetyl
l Carnitine Alpha lipoic acid combination, will it help you live longer?
What is the right dosage?
Information on acetyl l carnitine
for Alzheimer's disease
Acetylcarnitine (also
spelled acetyl-l-carnitine) and carnitine play important roles in the human body. These nutrients shuttle acetyl groups and fatty acids
into mitochondria for energy production. Without carnitine, fatty acids cannot easily
enter into mitochondria. The acetyl group of acetylcarnitine is used to form
acetyl-CoA, the most important intermediary in the generation of energy from
amino acids, fats, and carbohydrates. Therefore, acetylcarnitine serves as an
energy reservoir of acetyl groups and both acetylcarnitine and carnitine help improve energy production. The acetyl
group of acetylcarnitine is also used to make the important brain chemical
acetylcholine. Some studies suggest that perhaps acetylcarnitine can even act as a neurotransmitter itself.
Those who take carnitine pills notice an
increase in physical energy levels, but not as much mental energy. Acetylcarnitine has a significantly more
immediate and noticeable mental effect than carnitine. The proper dosage of
these nutrients depends on the individual using them and the purpose of their
use. For long term daily intake, we suggest using less than 100 mg daily. For
occasional use, a person can take up to 500 mg of these supplements. If you have an interest
in losing weight, perhaps even two or three pounds a week, consider doctor formulated
Diet Rx which includes these nutrients.
Acetyl L Carnitine 300 mg
.

Acetyl l Carnitine Supplement
300 mg
Acetyl l carnitine alpha lipoic
acid combination
Acetyl l carnitine and alpha lipoic acid are two nutrients that you may find
together in supplement form. There are various products that have a combination
of acetyl l carnitine alpha lipoic acid, and these include Juvenon and NSI.
There is no human research that says taking the high dosages of acetyl l
carnitine 500 mg alpha lipoic acid 200 mg provides health benefits or increases
life span. In our opinion, these dosages are too high and may actually be
counterproductive. There is no human research that says the combination of these
two supplements will help you live longer. If you want to take them for anti
aging benefits, use very low dosages and take days off.
Juvenon has acetyl l carnitine 500 mg alpha lipoic acid 200 mg per capsule along
with calcium and biotin.
NSI has acetyl l carnitine 500 mg and alpha lipoic acid 300 mg per capsule.
Juvenon is a patented cellular health supplement.
Source Naturals has acetyl l carnitine 500 mg and alpha lipoic acid 150 mg per
capsule
Arthritis Support has acetyl l carnitine 500 mg and alpha lipoic acid 150 mg per
capsule
Doctor's Trust has acetyl l carnitine 500 mg and alpha lipoic acid 200 mg per
capsule.
Acetyl l carnitine Research shows:
In aging rats, chronic administration of acetylcarnitine
increases cholinergic synaptic transmission and consequently enhances learning capacity.
The memory of aging rats is rejuvenated by giving them a combination of acetylcarnitine
and lipoic acid.
Potential Benefits of Acetylcarnitine according to
published studies:
Acetylcarnitine may improve mental fatigue in those who suffer from chronic
fatigue syndrome
Patients with multiple sclerosis are helped by acetylcarnitine, which reduces
their fatigue.
Acetylcarnitine is a promising treatment for those with diabetic neuropathy
May be helpful in geriatric patients with mild depression.
Acetylcarnitine improves the function of mitochondria, the organelles within
cells that are involved in energy production.
Acetylcarnitine is suitable for clinical use in the prevention of neuronal death after
peripheral nerve trauma.
May be helpful in those with Alzheimer's disease. Acetylcarnitine protects against amyloid-beta neurotoxicity.
A combination of
hoodia, ginger, green tea
extract, spirulina, acetylcarnitine, and several other herbs and nutrients, as
found in Diet Rx, is very effective for
weight loss.
Pancreatitis
Acetyl-L-carnitine ameliorates caerulein-induced acute pancreatitis in rats.
Basic Clin Pharmacol Toxicol. 2009 Jul; Arafa HM, Hemeida RA, Hassan MI,
Abdel-Wahab MH, Badary OA, Hamada FM. Department of Pharmacology and Toxicology,
Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
In the present study, we have addressed the possible protective role of
acetyl-L-carnitine in caerulein-induced acute pancreatitis in male Swiss albino
rats. Acute pancreatitis paradigm was developed by challenging animals with a
supramaximal dose of caerulein (20 microg/kg, SC) four times at hourly
intervals. Caerulein induced acute pancreatitis that was well-characterized
morphologically and biochemically. Severe oedema with marked increased relative
pancreatic weight, marked atrophy of acini with increased interacinar spaces,
vacuolization, and extensive leucocytic infiltration were diagnostic
fingerprints of the pancreatitis phenotype. A biochemical test battery that
confirmed the model comprised increased plasma amylase and lipase activities,
calcium levels as well as increased pancreatic enzymatic myeloperoxidase and
glutathione-S-transferase activities, beside increased pancreatic contents of
nitric oxide and malondialdehyde and reduced pancreatic glutathione level. Prior
administration of acetyl-L-carnitine (200 mg/kg, IP) for seven consecutive days
ahead of caerulein challenge alleviated all the histological and biochemical
manifestations of acute pancreatitis. These results suggest a possible
protective role of the carnitine ester in such a murine acute pancreatitis model
probably via regulation of the oxidant/antioxidant balance, beside modulation of
the myeloperoxidase and nitric oxide systems, which are involved in the
inflammatory cascade that most often associate the disease.
Acetyl l carnitine alpha lipoic
side effects
The mind boosting effect of acetylcarnitine is often noticed within a few
hours, or even within an hour. Most people report feeling mentally sharper,
having more focus and being more alert. Some find a mild mood enhancement.
Acetylcarnitine may be used as an overall mind booster. The typical dosage is 250
to 500 mg
once a day, preferably in the early part of the day. Side effects of overstimulation may occur at dosages greater
than 300 to 500 mg. Same with alpha lipoic acid, side effects of insomnia can
occur over 50 mg or 100 mg.
Acetyl carnitine alpha lipoic
acid questions
Q. I took a combination of acetyl l carnitine 500 mg alpha lipoic acid 200 mg in
a pill form called Juvenon and felt wired all day with insomnia. I'm feeling
tired and have lack of sleep. Is Juvenon supposed to make me healthier?
A. High doses of many supplements can make one unhealthy rather
than improve health.
Does acetylcarnitine help with erection? Are
there other herbs that can help?
Acetylcarnitine may help some, but
there are several herbs you can review at this
impotence page.
Supplements and Herbal Index tongkat ali home page