Acetyl l Carnitine Alpha lipoic acid combination, will it help you live longer? What is the right dosage?
Information on acetyl l carnitine for Alzheimer's disease

Acetylcarnitine (also spelled acetyl-l-carnitine) and carnitine play important roles in the human body. These nutrients shuttle acetyl groups and fatty acids into mitochondria for energy production. Without carnitine, fatty acids cannot easily enter into mitochondria. The acetyl group of acetylcarnitine is used to form acetyl-CoA, the most important intermediary in the generation of energy from amino acids, fats, and carbohydrates. Therefore, acetylcarnitine serves as an energy reservoir of acetyl groups and both acetylcarnitine and carnitine help improve energy production. The acetyl group of acetylcarnitine is also used to make the important brain chemical acetylcholine. Some studies suggest that perhaps acetylcarnitine can even act as a neurotransmitter itself.
   Those who take carnitine pills notice an increase in physical energy levels, but not as much mental energy. Acetylcarnitine has a significantly more immediate and noticeable mental effect than carnitine. The proper dosage of these nutrients depends on the individual using them and the purpose of their use. For long term daily intake, we suggest using less than 100 mg daily. For occasional use, a person can take up to 500 mg of these supplements. If you have an interest in losing weight, perhaps even two or three pounds a week, consider doctor formulated Diet Rx which includes these nutrients.

Acetyl L Carnitine 300 mg
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Additional products formulated by Dr. Sahelian include Passion Rx (for sexual enhancement in men and women), Eyesight Rx (better vision within hours), Prostate Power Rx, Joint Power Rx, and Mind Power Rx.

Acetyl l Carnitine Supplement 300 mg


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Acetyl l carnitine alpha lipoic acid combination
Acetyl l carnitine and alpha lipoic acid are two nutrients that you may find together in supplement form. There are various products that have a combination of acetyl l carnitine alpha lipoic acid, and these include Juvenon and NSI. There is no human research that says taking the high dosages of acetyl l carnitine 500 mg alpha lipoic acid 200 mg provides health benefits or increases life span. In our opinion, these dosages are too high and may actually be counterproductive. There is no human research that says the combination of these two supplements will help you live longer. If you want to take them for anti aging benefits, use very low dosages and take days off.

Juvenon has acetyl l carnitine 500 mg alpha lipoic acid 200 mg per capsule along with calcium and biotin.
NSI has acetyl l carnitine 500 mg and alpha lipoic acid 300 mg per capsule. Juvenon is a patented cellular health supplement.
Source Naturals has acetyl l carnitine 500 mg and alpha lipoic acid 150 mg per capsule
Arthritis Support has acetyl l carnitine 500 mg and alpha lipoic acid 150 mg per capsule
Doctor's Trust has acetyl l carnitine 500 mg and alpha lipoic acid 200 mg per capsule.

Acetyl l carnitine Research shows:
In aging rats, chronic administration of acetylcarnitine increases cholinergic synaptic transmission and consequently enhances learning capacity. The memory of aging rats is rejuvenated by giving them a combination of acetylcarnitine and lipoic acid.

Potential Benefits of Acetylcarnitine according to published studies:
Acetylcarnitine may improve mental fatigue in those who suffer from chronic fatigue syndrome
Patients with multiple sclerosis are helped by acetylcarnitine, which reduces their fatigue.
Acetylcarnitine is a promising treatment for those with diabetic neuropathy
May be helpful in geriatric patients with mild depression.
Acetylcarnitine improves the function of mitochondria, the organelles within cells that are involved in energy production.
Acetylcarnitine is suitable for clinical use in the prevention of neuronal death after peripheral nerve trauma.
May be helpful in those with Alzheimer's disease. Acetylcarnitine protects against amyloid-beta neurotoxicity.
A combination of hoodia, ginger, green tea extract, spirulina, acetylcarnitine, and several other herbs and nutrients, as found in Diet Rx, is very effective for weight loss.

Pancreatitis
Acetyl-L-carnitine ameliorates caerulein-induced acute pancreatitis in rats.
Basic Clin Pharmacol Toxicol. 2009 Jul; Arafa HM, Hemeida RA, Hassan MI, Abdel-Wahab MH, Badary OA, Hamada FM. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
In the present study, we have addressed the possible protective role of acetyl-L-carnitine in caerulein-induced acute pancreatitis in male Swiss albino rats. Acute pancreatitis paradigm was developed by challenging animals with a supramaximal dose of caerulein (20 microg/kg, SC) four times at hourly intervals. Caerulein induced acute pancreatitis that was well-characterized morphologically and biochemically. Severe oedema with marked increased relative pancreatic weight, marked atrophy of acini with increased interacinar spaces, vacuolization, and extensive leucocytic infiltration were diagnostic fingerprints of the pancreatitis phenotype. A biochemical test battery that confirmed the model comprised increased plasma amylase and lipase activities, calcium levels as well as increased pancreatic enzymatic myeloperoxidase and glutathione-S-transferase activities, beside increased pancreatic contents of nitric oxide and malondialdehyde and reduced pancreatic glutathione level. Prior administration of acetyl-L-carnitine (200 mg/kg, IP) for seven consecutive days ahead of caerulein challenge alleviated all the histological and biochemical manifestations of acute pancreatitis. These results suggest a possible protective role of the carnitine ester in such a murine acute pancreatitis model probably via regulation of the oxidant/antioxidant balance, beside modulation of the myeloperoxidase and nitric oxide systems, which are involved in the inflammatory cascade that most often associate the disease.


Acetyl l carnitine alpha lipoic side effects
The mind boosting effect of acetylcarnitine is often noticed within a few hours, or even within an hour. Most people report feeling mentally sharper, having more focus and being more alert. Some find a mild mood enhancement. Acetylcarnitine may be used as an overall mind booster. The typical dosage is 250 to 500 mg once a day, preferably in the early part of the day. Side effects of overstimulation may occur at dosages greater than 300 to 500 mg. Same with alpha lipoic acid, side effects of insomnia can occur over 50 mg or 100 mg.

Acetyl carnitine alpha lipoic acid questions
Q. I took a combination of acetyl l carnitine 500 mg alpha lipoic acid 200 mg in a pill form called Juvenon and felt wired all day with insomnia. I'm feeling tired and have lack of sleep. Is Juvenon supposed to make me healthier?
   A. High doses of many supplements can make one unhealthy rather than improve health.

Does acetylcarnitine help with erection? Are there other herbs that can help?
    Acetylcarnitine may help some, but
there are several herbs you can review at this impotence page.

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