Arcoxia drug etoricoxib
Arcoxia is a
pharmaceutical drug
made by Merck & Co. Arxocia is promoted as causing fewer side effects such as stomach disorders and complications than some older painkillers.
COX-2
inhibitors were designed as a safer long-term alternative to NSAIDs but have
been linked with an increased risk of heart attacks. Vioxx, an older COX-2
inhibitor also made by Merck, was pulled from the market in 2004 after research
showed it doubled the risk of heart attack and stroke in people who took it for
at least 18 months.
Arcoxia is COX-2 inhibitor
Arcoxia is a COX-2 inhibitor while diclofenac belongs to an older class of
therapies known as non-steroidal anti-inflammatory drugs or NSAIDs, which
includes aspirin and ibuprofen. "Our results indicate that the rate of
clinically important upper gastrointestinal events was lower with the COX-2
selective inhibitor etoricoxib than it was with the traditional NSAID diclofenac,"
said Dr. Loren Laine of the University of Southern California Keck School of
Medicine in Los Angeles. There were fewer ulcers in patients taking the new drug
and more patients continued to take the treatment, she added. A study published
in November 2006 found Arcoxia did not raise heart risks as compared to
diclofenac, but Dr. Steve Nissen, an expert on such drugs at the Cleveland
Clinic in Ohio, questioned whether it was useful to compare a new drug to
diclofenac, which is known to cause many side-effects.
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