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Terminalia arjuna research and use to lower cholesterol
Feb 27 2014
Ancient Indian Medical knowledge known as Ayurveda goes back millennia. The Vedas and Puranas refer various materials of medical importance including herbs, plants and trees, etc. Ancient medical scientists have mentioned the properties of Arjuna. Modern research has discovered that it has antioxidant properties and may be clinically helpful in patients with angina.
Buy Arjuna, 550 mg,
Serving Size 1 Tablet
buy Terminalia arjuna Bark - 500 mg each pill and 50 mg of a 10 to 1 standardized extract
Suggested use: Take one Arjuna tablet once a day or as recommended by your health care provider.
The arjuna bark extract contains acids (arjunic acid, terminic acid), glycosides (arjunetin arjunosides), strong antioxidants (flavones, tannins, oligomeric proanthocyanidins), and minerals.
Efficacy of Terminalia arjuna in chronic stable angina: a double-blind, placebo-controlled, crossover study comparing with isosorbide mononitrate.
Indian Heart J. 2002.
Terminalia arjuna (500 mg 8 hourly), isosorbide mononitrate (40 mg/daily) or a matching placebo for one week each, separated by a wash-out period of at least three days in a randomized, double-blind, crossover design. They underwent clinical, biochemical and treadmill exercise evaluation at the end of each therapy which were compared during the three therapy periods. Therapy was associated with significant decrease in the frequency of angina and need for isosorbide dinitrate. The treadmill exercise test parameters improved significantly during therapy compared to those with placebo. Terminalia arjuna bark extract, 500 mg 8 hourly, given to patients with stable angina with provocable ischemia on treadmill exercise, led to improvement in clinical and treadmill exercise parameters as compared to placebo therapy.
Cytotoxic agents in this plant include arjunic acid, arjungenin, arjunetin and arjunoglucoside I.
Compounds in the plant lower cholesterol and have antioxidant properties.
Arjuna has compounds that protect against DNA damage from toxins.
Antimutagenic activities of acetone and methanol fractions of Terminalia arjuna.
Food Chem Toxicol. 2002.
Terminalia arjuna, an Indian medicinal plant, has been reported to have beneficial effects in patients with ischemic heart disease in a number of small, open studies. Those with serious heart disease should not use certain herbs such as tongkat ali.
Arjunolic acid, a triterpene and a potent principle from the bark, has been shown to provide significant cardiac protection in isoproterenol induced myocardial necrosis in rats. Arjunolic acid treatment prevents the decrease in the levels of superoxide dismutase, catalase, glutathione peroxidase, ceruloplasmin, alpha-tocopherol, reduced glutathione (GSH), ascorbic acid, lipid peroxide, MPO and the cardioprotection is confirmed by the histopathological studies. This study shows that the cardioprotection of arjunolic acid pre and post treatment could possibly be due to the protective effect against the damage caused by myocardial necrosis.
No major risk or safety issues have been mentioned in the medical literature regarding the use of this herb.
Compounds found in arjuna
A triterpene glycoside, arjunetoside, together with oleanolic and arjunic acids, and a cardenolide, have been isolated from the root bark. Two new oleanane-type triterpene glycosides designated as Termiarjunoside I and Termiarjunoside II were isolated from stem bark. Both compounds potently suppressed the release of nitric oxide and superoxide from macrophages and also inhibited aggregation of platelets.
Availability as supplement
Should I worry about the authenticity of terminalia arjuna bark or its extract in a supplement bottle?
There is never a guarantee that any product you buy will be true to the label, but in a large majority of cases supplement makers are honest about the herbal products.