Autism information and alternative treatment, new research review and suggestions on dietary supplements

Autism is the fastest growing developmental disorder in the United States. In 2006 more children will be diagnosed with autism than AIDS, diabetes and cancer combined, yet profound gaps remain in our understanding of both the causes and cures of the disorder. Increasing our knowledge about developmental disruptions in individuals with autism spectrum disorder is crucial, since early detection and intervention can lead to improved outcomes in individuals with autism spectrum disorder. Infants who don't respond to their name by 1 year of age appear to be more likely to be diagnosed with an autism spectrum disorder or other developmental problem by the age of 2.

Autistic disorder, or autism, is a developmental disorder resulting in social, language, or sensorimotor deficits, occurs in approximately seven of 10,000 persons. Early detection and intervention significantly improve outcome, with about one third of autistic persons achieving some degree of independent living. Indications for developmental evaluation include no babbling, pointing, or use of other gestures by 12 months of age, no single words by 16 months of age, no two-word spontaneous phrases by 24 months of age, and loss of previously learned language or social skills at any age. Autism is frequently associated with fragile X syndrome and tuberous sclerosis, and may be caused by lead poisoning and metabolic disorders. Autistic children often suffer form mental retardation, seizure disorder, and psychiatric disorders such as depression and anxiety.
   Advanced maternal age and paternal age are both risk factors for having a child with an autism spectrum disorder. However, the risk of having a child with autism is very small, even for the oldest parents.

Natural options for the treatment of Autism
There is a scattering of research that indicates diet and nutrients may be of some benefit in treating autism, but  much more research is needed before we have a better understanding the role of diet and nutritional supplements in the therapy of this condition.

Children given carnosine showed statistically significant improvements on several tests including an improvement in vocabulary and recognizing a picture. You can buy
Carnosine supplement online.

Thanks for your time in reading this email. My son is two and a half years old and has no speech,  has hyperactivity and is very sensory seeking. OAT test shows mitochondria dysfunction. I will like to go the natural route to help him. What supplements can I give him?.

Carnosine Helpful in Autism treatment
From the day she was born, Betty seemed different from other infants. At an age when most infants enjoy interacting with people and exploring their environment, Betty sat motionless in her crib and didn't respond to rattles or other toys. It wasn’t too long before Betty was diagnosed with autism. Unfortunately, modern medicine has little to offer as a cure for this condition. But supplements may be helpful. Researchers at the Autism and Epilepsy Specialty Services in Lake Bluff, Illinois, investigated 31 children with autism in an 8-week, double-blinded study to determine if carnosine would result in changes. Carnosine is a natural substance composed of 2 amino acids. It is found in relatively high concentrations in several body tissues, muscles, and nerve tissue, including the brain. The exact role of carnosine is not well understood, but studies indicate that this nutrient has antioxidant potential and may also act as a neurotransmitter (chemical messenger in the nervous system). The children received 800 mg of carnosine a day and were compared with a group of children on placebo. After 8 weeks, children given carnosine showed statistically significant improvements on several tests including an improvement in vocabulary and recognizing a picture.
     Comments: Carnosine, also known as L-carnosine, is sold in health food stores most commonly in capsules of 500 mg. It would be worthwhile to try 100 to 200 mg of this nutrient before breakfast and lunch for a few weeks under a pediatrician’s supervision.

Diagnosis of autism
Early detection of autism is critical for early intervention, yet autism spectrum disorders (ASD) are typically not diagnosed until after three years of age. However, differences between typically developing children and those with ASD are detectable by two years of age. Because there are currently no medical diagnostic tests for autism, identifying developmental disruptions in infants and very young children with ASD may allow for earlier detection and critical intervention. A study examined development in 87 infants at 6, 14 and 24 months of age using a standardized development test. Based on data and clinical judgment at 24 months, participants were classified as: unaffected, language delayed (LD) or ASD. Researchers compared development across groups at the three target ages and observed statistically significant differences between the autism spectrum disorders group and the unaffected group at 14 months. By 24 months, significant differences were detectable between the ASD group and both the unaffected and LD groups. Participants in the study included infants at high risk for autism (siblings of children with autism), and infants at low risk (no family history of autism). Researchers measured development using the Mullen Scales of Early Learning (MSEL), a standardized test which assesses five domains of development, including: gross and fine motor; visual reception; and receptive and expressive language. At 14 months, four of the five mean MSEL scores were significantly lower in toddlers with autism spectrum disorder than those in the unaffected group. By 24 months, the ASD group performed significantly worse than the unaffected group in all domains of development, and worse than the LD group in three domains. Nearly half of the ASD group showed developmental worsening between 14 and 24 months. This study and previous research studies conducted by Dr. Landa found that developmental red flags for parents and physicians to watch for include: poor eye contact; reduced responsive smiling; diminished babbling; reduced social responsivity; and difficulty with language development, play and initiating or sustaining social interaction. Kennedy Krieger Institute.

Medical and prescription medication treatment
Kids with autism don't benefit from treatment with the popularly prescribed antidepressant citalopram. The study, published in the June 2009 issue of Archives of General Psychiatry, is the first to show that citalopram doesn't reduce repetitive behaviors that are a key characteristic of autism and are a significant reason why this class of antidepressants is prescribed. Children with autism-spectrum disorders often exhibit repetitive behaviors, including motor symptoms like flapping or rocking, or overly focusing on topics of intense interest. They can be inflexible or become agitated if asked to stop the behaviors. Antidepressants known as selective serotonin reuptake inhibitors, or SSRIs, are thought to be helpful for these symptoms because they benefit children with obsessive-compulsive disorder, who also exhibit repetitive behaviors. But the effectiveness of antidepressants for children with autism hadn't been well-studied.

Genetic basis for autism
French scientists have identified genetic mutations in a small number of children with autism which could provide insight into the biological basis of the disorder. They sequenced a gene called SHANK3 in more than 200 people with autism spectrum disorders (ASD), which includes autism, and found mutations in the gene in members of three families. ASD covers a range of problems that affect communication, social interaction, verbal skills and behavior.

Age of mother and father as risk factors
Children born to older mothers or fathers may have a higher risk of autism than those with younger parents. In a study of 7.5 million births in California between 1989 and 2002, researchers at the state's health department found that a child's risk of developing autism increased along with the age of the parents. For each 10-year increase in a mother's age between the ages of 20 and 40, the risk of her child developing autism increased by 38 percent. Similarly, each 10-year increase in a father's age between the ages of 20 and 60 was associated with a 22-percent increase in autism risk. The findings add to a conflicting body of research on what role, if any, parents' age plays in autism development. Past studies have either found that older age may increase the risk, or has no impact at all. American Journal of Epidemiology, November 1, 2009.

Brain imaging and autism
Autistic children have more gray matter in areas of the brain that control social processing and sight-based learning than children without the developmental disability. Autistic children have enlarged gray matter in the parietal lobes of the brain linked to the mirror neuron system of cells associated with empathy, emotional experience and learning through sight.

Testosterone and autism
According to Simon Baron-Cohen, director of the Autism Research Centre at Britain's Cambridge University, children exposed to high levels of testosterone in the womb show more autism related traits later in life. Higher levels of testosterone may contribute to autism.

Autism autistic child questions
I am just writing to ask you how much of the Carnosine, and fish oil to give my 10 year old autistic child (Boy). I know you mention in your website that a child should take less than an adult but i don't know how much less. I will be meeting with my son's neurologist this week to start monitoring him and first of all get his "OK" since my son is on anticonvulsants. My autistic child is non-verbal (with potential) and very much dependant on me for his overall needs.
    It is difficult to know how any child responds to medicines or supplements. As a general rule, it is a good idea to start with a quarter of the adult dose for carnosine and one or two fish oil capsules a day and then your doctor would monitor.

I have 2 autistic grandchildren 7 and 9 years old, both been diagnosed as having mild AUTISM. The 9 year old started talking at 6, he is academically a bright boy, his speech is sometimes interrupted and repetitive. Marcus the 7 year old has only few words, no sentenses he is also a bright boy but he can't talk and express himself starts crying followed by autistic behaviours. Their mother been seeing a local doctor for the last 2 years, both boys went trough extensive medical examinations, dieting and different supplements which helped very little. I've been doing lot of web searching on Autism, when I got across your site and saw the MIND-POWER-Rx capsules, I taught I'll email you with a question. Can I purchase MIND-POWER-Rx or any other supplement that you can recomend to help improve these kids conditions specially the 7 year old speechless boy.
    It is difficult to predict the response of any child or adult to a supplement. Perhaps some of the supplements listed on this page can be tried to see if there is any benefit.

I am intrested in learning more about the health benefits of dmg. I heard from a t.v. info-mertial that it may benefit individuals who live with autism and like conditions ,would you please comment on this.
    One study back in 1999 did not show benefit with the use of this supplement in relation to autism and the treatment of this condition.

Can tegretol and mellaril cause elevated GGT levels and borderline abnormal QTc (higher) numbers.  What besides homeopathy and supplements can be helpful for treatment of autistic disorder, have used homeopathy for many years 74 to be exact and supplements for about 15 years, My concern is about autistic individuals on necessary meds due to aggressive behaviors.

Supplements and Herbal Index