Butterbur plant butterbur root, butterbur herb for allergy (Petasites hybridus)

Butterbur is a shrub found throughout Europe as well as parts of Asia and North America. Butterbur that has been used medicinally for centuries to treat cough, asthma, and skin wounds. The plant can grow to a height of three feet and is usually found in wet, marshy ground, in damp forests, and adjacent to rivers or streams. For more butterbur research. Quercetin may also be helpful in some cases of allergy.

Petadolex ( Butturbur ) 60 Softgels - Enzymatic Therapy

Petadolex contains the patented extract of butterbur that supports healthy blood vessel tone in the brain, as well as normal blood flow in the brain.* Butterbur has been the subject of several placebo-controlled clinical studies.

Petadolex is standardized to contain 15% of butterbur's key ingredient, petasin. It's also guaranteed to be pyrrolizidine alkaloid (PA) free, so you can use it with confidence. PA's are toxic compounds that can harm the liver. Studies demonstrate patented Petadolex is safe and well tolerated.

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Active ingredients in Butterbur
Petasin, a kind of sesquiterpene ester, appears to be a major active compound of Butterbur extract. It has inhibitory activities on leukotriene generation in eosinophils and neutrophils. This indicates that it may have anti-inflammatory and anti-allergy properties. Butterbur may be helpful for seasonal allergic rhinitis. Butterbur also helps reduce smooth muscle spasm.

Medical uses for Butterbur

Migraine Headache: Two clinical studies using 50 mg and 75 mg of a standardized Butterbur extract twice daily for 12 weeks demonstrated its effectiveness as a prophylactic treatment for migraines. When used to treat migraines, administration is prophylactic and supplementation should be carried out daily for a few weeks and then tapered until migraine incidence begins to increase. Butterbur may work by preventing peptidoleukotriene biosynthesis.

Asthma and Bronchitis: Various parts of the Butterbur plant have been used for centuries to treat bronchial asthma and whooping cough. Butterbur's possible effectiveness in treating respiratory disorders such as asthma and bronchitis is attributed to the antispasmodic and anti-inflammatory properties of the petasin constituent. (see below)

Gastrointestinal Disorders: A German study found extracts of Butterbur blocked ethanol-induced gastric damage and reduced ulcerations of the small intestine caused by indomethacin, an anti-inflammatory drug used to treat arthritic conditions. The results of this study were attributed to inhibition of lipoxygenase activity and leukotriene biosynthesis.

Butterbur Safety
Butterbur has not been studied extensively enough to determine its side effects.

Butterbur Dosage
Typically, Butterbur extracts are standardized to contain a minimum of 7.5 mg of petasin and isopetasin. The adult dosage ranges from 50-100 mg twice daily with meals.

Enzymatic Therapy - Petadolex, 60 Softgels
 Petadolex contains the patented extract of butterbur that supports healthy blood vessel tone in the brain, as well as normal blood flow in the brain.* It has been the subject of two placebo-controlled clinical studies. Petadolex is standardized to contain 15% of butterbur's key ingredient, petasin. It's also guaranteed to be pyrrolizidine alkaloid (PA) free, so you can use it with confidence. PA's are toxic compounds that can harm the liver. Studies demonstrate patented Petadolex is safe and well tolerated.

Butterbur Research Update
Petasites hybridus (Butterbur root) extract in the treatment of asthma - an open trial.
Danesch UC. University of Heidelberg, Germany; past research position, Stanford School of Medicine; Research and development, Weber and Weber. Correspondence address: Muenchner Strasse 13, D-82061, Neuried, Germany.
Altern Med Rev. 2004 Mar;9(1):54-62.

 A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis. Lee DK, Gray RD, Robb FM et al. Clin Exp Allergy. 2004;34:646-9.

Safety of a patented special butterbur root extract for migraine prevention.
Danesch U, Rittinghausen R. Weber and Weber, Inning, Germany. Headache. 2003 Jan;43(1):76-8.

Butterbur questions
Q. My wife has been having pains due to cancer and chemo and surgery and soon to have radiation. She has all sorts of pains everywhere. Can butterbur help? Or is there something better?
   A. We cannot predict what kind of effect butterbur will have on cancer related pain.
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