CLA for losing weight - does CLA work for weight loss?

Conjugated linoleic acid (CLA) is a slightly altered form of the essential fatty acid linoleic acid. Some studies, mostly in rodents, have shown that CLA could help reduce weight but others have shown conflicting results. The latest human study shows that a year treatment with CLA reduces body fat in overweight adults. It's possible that CLA could be effective as a weight loss supplement but I'm not yet totally convinced. For a natural sugar alternative that you can substitute instead of sugar and consumer fewer calories, see stevia benefit information.

CLA supplement, 750 mg, 50 softgels - Club Natural

CLA (conjugated linoleic acid) is a recently recognized supplement. CLA is found naturally in a variety of foods, including dairy. CLA offers a rich source of conjugated linoleic acid to supplement the diet naturally.

Each capsule provides 750 mg CLA supplement.
Directions: Take 1, 2 or 3  CLA softgels daily or as recommended by your health care provider.

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Diet Rx
A combination of hoodia, ginger, cinnamon, green tea extract, spirulina, acetyl-l-carnitine, choline, guggul, and several other herbs and nutrients, as found in Diet Rx, is a very effective herbal diet pill for weight loss. Users of Diet Rx have lost several pounds within a week or two. Diet Rx does not have CLA. FREE Diet Rx Bottle

Here is a list of supplements that suppress appetite, help with weight loss, manage cholesterol levels, or improve metabolic syndrome. Many of these are found in a product called Diet Rx
Ginger root (Zingiber officinalis), Green-Tea-Extract (Camellia sinensis, standardized to contain 50% polyphenols), Spirulina (Spirulina platensis), Hoodia-Extract (Hoodia gordonii, 20 to 1 extract), CLA fatty acids, Cinnamon root (Cinnamomum cassia), Apple-Cider-Vinegar, Apple pectin, Garcinia Cambogia CitriMax HCA-600 SXS (standardized to contain 60% hydroxycitric acid), Glucomannan konjac 4 to 1 extract, Alpha-Lipoic, Grapefruit extract (Citrus paradise, 4 to 1 extract), Acetyl-l-Carnitine. Banaba extract (standardized to contain 1 % corosolic acid), 5-HTP, Choline bitartrate, Inositol, Carnitine (Hcl), Pomegranate (standardized to contain 40 % ellagic acid), Bitter melon extract (Momordica charantia), Psyllium husk, Coleus forskohlii (standardized to contain 10 % Forskolin ), Fenugreek seed extract 4 to 1 (Trigonella foenum), Guggul herb (standardized to contain 10 % guggulsterones), and Inulin. Other products to consider include chitosan. We don't think guarana is a good choice. Yerba mate may be helpful in combination with other herbs.

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CLA fatty acids
The term conjugated linoleic acid CLA refers to several conjugated dienoic isomers of linoleic acid, of which the trans-10,cis-12 isomer has been reported to reduce fat tissue and increase lean mass in mice and other animals. However, most dietary CLA in humans is obtained from dairy products, accounting for the cis-9,trans-11 CLA isomer, also known as rumenic acid, for more than 90% of the total CLA intake. Commercial CLA preparations industrially produced, containing trans-10,cis-12 and cis-9,trans-11 CLA isomers in diverse proportions, are attracting consumers' interest because of the purported body fat-lowering effects of CLA.


CLA Research update
Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans
Jean-Michel Gaullier, American Journal of Clinical Nutrition, Vol. 79, No. 6, 1118-1125, June 2004
CLA may reduce body fat mass (BFM) and increase lean body mass (LBM), but the long-term effect of CLA was not examined. The objective of the study was to ascertain the 1-y effect of CLA on body composition and safety in healthy overweight adults consuming an ad libitum diet. Male and female volunteers (n = 180) with body mass indexes (in kg/m2) of 25–30 were included in a double-blind, placebo-controlled study. Subjects were randomly assigned to 3 groups: CLA -free fatty acid (FFA), CLA triacylglycerol, or placebo (olive oil). Results: Mean (± SD) BFM in the CLA-triacylglycerol and CLA - FFA groups was 8.7 ± 9% and 6.9 ± 9%, respectively, lower than that in the placebo group. Subjects receiving CLA - FFA had 1.8 ± 4.3% greater LBM than did subjects receiving placebo. These changes were not associated with diet or exercise. LDL increased in the CLA FFA group, HDL decreased in the CLA-triacylglycerol group, and lipoprotein(a) increased in both CLA groups compared with month 0. Fasting blood glucose concentrations remained unchanged in all 3 groups. Glycated hemoglobin rose in all groups from month 0 concentrations, but there was no significant difference between groups. Conclusion: Long-term supplementation with CLA - FFA or CLA - triacylglycerol reduces BFM in healthy overweight adults.

The effect of conjugated linoleic acid (CLA) supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects.
Kamphuis MM, Maastricht University, The Netherlands. Int J Obes Relat Metab Disord. 2003 Jul;27(7):840-7.

Effect of conjugated linoleic acid CLA on body composition and plasma lipids in humans: an overview of the literature.

Antonius HM,
Utrecht University, Utrecht, Netherlands.

CLA questions
Q. I'm a sixty two year old male, 192 in weight, started taking cla about half a month ago, to lose weight. I also go to a gym began in September of this year. Read an article about cla by Dr. Sahelian,  I feel CLA isn't what I should be taking after reading the cla article. I got cla from a company called NOW foods.
   A. Thus far we are not impressed by CLA. We await further research for more results to see whether CLA really works and whether it is worth the cost.

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