CoQ10 dosage in
capsule or softgel, 30 mg, 60 mg, safety and risks, does it help with hypertension
or blood pressure?
CoQ10 is a naturally occurring nutrient found in each cell of the
body. CoQ10 was first identified by University of Wisconsin researchers in 1957. CoQ10 is
found in foods, particularly in fish and meats. In addition to playing a significant role
in the energy system of each of our cells, CoQ10 is a good antioxidant. Many who
take CoQ10 notice that this nutrient enhances energy and mental clarity.
Alpha lipoic acid is another
excellent antioxidant that can be taken in dosages less than 50 mg 2 or three
times a week with a low dose of the coenzyme supplement.
CoQ10 on sale --
30mg, 50 mg,
60mg, and 100 mg
CoQ10 - 50 mg, 60 softgels
CoQ10 - 100 mg, 60 softgels
For which conditions is CoQ10 helpful?
Studies with CoQ10 have mostly focused on its
role in improving certain types of cardiovascular diseases, including congestive
heart
failure and hypertension. However, CoQ10 may also benefit those with diabetes and
Parkinson's disease.
Those on a
vegetarian diet should consider taking a CoQ10 supplement. The benefits of
this supplement in reducing blood pressure are not significant and cannot be
relied on. There are more effective supplements to treating hypertension.
Infertility
COENZYME Q10 AND MALE INFERTILITY.
J Endocrinol Invest. 2009 May 21. Balercia G, Mancini A, Paggi F, Tiano
L, Pontecorvi A, Boscaro M, Lenzi A, Littarru GP. Endocrinology, Andrology Unit,
Dept of Clinical Medicine and Applied Biotechnologies, Polytechnic University of
Marche, Umberto I Hospital, Ancona, Italy.
We had previously demonstrated that Coenzyme Q10 (also commonly called
ubiquinone) is present in well measurable levels in human seminal fluid, where
it probably exerts important metabolic and antioxidant functions; seminal CoQ10
concentrations show a direct correlation with seminal parameters (count and
motility). Alterations of CoQ10 content were also shown in conditions associated
with male infertility, such as asthenozoospermia and varicocele (VAR). The
physiological role of this molecule was further clarified by inquiring into its
variations in concentrations induced by different medical or surgical procedures
used in male infertility treatment. We therefore evaluated CoQ10 concentration
and distribution between seminal plasma and spermatozoa in varicocele, before
and after surgical treatment, and in infertile patients after rh-FSH therapy.
The effect of CoQ10 on sperm motility and function had been addressed only
through some in vitro experiments. In two distinct studies conducted by our
group, twenty-two and sixty patients affected by idiopathic asthenozoospermia
were enrolled respectively. CoQ10 and its reduced form, ubiquinol, increased
significantly both in seminal plasma and sperm cells after treatment, as well as
spermatozoa motility. A weak linear dependence among the relative variations, at
baseline and after treatment, of seminal plasma or intracellular coenzyme Q10,
ubiquinol levels and kinetic parameters was found in the treated group. Patients
with lower baseline value of motility and CoQ10 levels had a statistically
significant higher probability to be responders to the treatment. In conclusion,
the exogenous administration of CoQ10 increases both ubiquinone and ubiquinol
levels in semen and can be effective in improving sperm kinetic features in
patients affected by idiopathic asthenozoospermia.
How does CoQ10 work?
Each cell in the body needs a source of energy to survive, so cells break
down sugars, fats, and amino acids to make energy. Small enclosures within cells that make
this energy are called mitochondria. CoQ10 exists naturally in our mitochondria and
carries electrons involved in energy metabolism. CoQ10 is essential in the production of
adenosine triphosphate (ATP), the basic energy molecule of each cell.
In the bloodstream, CoQ10 is mainly transported
by lipoproteins such as LDL (low-density lipoprotein) and HDL (high-density lipoprotein).
It is thought that CoQ10 is one of the first antioxidants to be depleted when LDL is
subjected to oxidation. Hence, CoQ10 is an important nutrient that prevents the oxidation
of lipoproteins, thus potentially reducing the risk of arteries from forming plaques and
getting damaged.
In healthy individuals, CoQ10 is found in high
concentrations in the heart, kidneys, and liver.
Recommendations
CoQ10 is probably beneficial in cardiovascular conditions and this
nutrient will likely be found to play some positive role in cognitive or
neurodegenerative disorders, but more studies are needed. In
the meantime, it would seem appropriate to supplement with this nutrient as part
of a long-term health regimen, particularly for those with cardiovascular
conditions. Long-term therapy with 10 to 60 mg seems to be a reasonable option
for many individuals.
CoQ10 Absorption
Effect on absorption and oxidative stress of different oral CoQ10 dosages and
intake strategy in healthy men.
Biofactors. 2005;25(1-4):219-24. Halberg Hospital and Research Institute,
Moradabad, India.
The effect of various dosages and dose strategies of oral coenzyme CoQ10
administration on serum CoQ10 concentration and bioequivalence of various
formulations are not fully known. In a randomized, double
blind, placebo controlled trial 60 healthy men, aged 18-55 years, were
supplemented with various dosages and dose strategies of coenzyme CoQ10 soft oil
capsules (Myoqinon 100 mg, Pharma Nord, Denmark) or crystalline 100 mg CoQ10
powder capsules or placebo. After 20 days blood levels were compared and
oxidative load parameters, malondialdehyde (MDA) and thiobarbituric acid
reactive substances (TBARS) were monitored to evaluate bioequivalence. All the
subjects were advised to take the capsules with meals. Blood samples were
collected after 12 hours of overnight fasting at baseline and after 20 days of
CoQ10 administration. Compliance was evaluated by counting the number of
capsules returned by the subjects after the trial. RESULTS: Compliance by
capsule counting was >90%. Side effects were negligible. Serum concentrations of
CoQ10 (average for groups) increased significantly 3-10 fold in the intervention
groups compared with the placebo group. Serum response was improved with a
divided dose strategy. TBARS and MDA were in the normal ranges at baseline.
After 20 days intervention in the 200 mg group TBARS and MDA decreased, but the
decrease was only significant for MDA (Fig. 2). Conclusions: All
supplementations increased serum levels of CoQ10. CoQ10 dissolved in an oil
matrix was more effective than the same amount of crystalline CoQ10 in raising
CoQ10 serum levels. 200 mg of oil/soft gel formulation of CoQ10 caused a larger
increase in CoQ10 serum levels than did 100 mg. Divided dosages (2 x 100 mg) of
CoQ10 caused a larger increase in serum levels of CoQ10 than a single dose of
200 mg. Supplementation was associated with decreased oxidative stress as
measured by MDA-levels. Indians appear to have low baseline serum coenzyme CoQ10
levels which may be due to vegetarian diets. Further studies in larger number of
subjects would be necessary to confirm our findings.
History of CoQ10
CoQ-10’s was discovered in 1957. Frederick Crane, Ph.D., working at the
University of Wisconsin, isolated an orange substance from the mitochondria of
beef heart. The following year Karl Folkers, Ph.D., and coworkers at Merck
synthesized the orange molecule in the laboratory. Folkers played a role in
naming the substance CoQ-10.
Popularity of CoQ10
Retail sales data for year ending 2007indicate a 19% increase in dollar sales
volume and a 9% increase in unit sales of CoQ10. The data lists CoQ10 as the
third largest volume non letter vitamin in the vitamin and supplement category
behind Glucosamine / Chondroitin and Essential Fatty Acids. It is now estimated
there are approximately 6,000,000 U.S. consumers supplementing an average of
82mg CoQ10 daily.
CoQ10 article
Many people who take CoQ10 notice an increase in energy. But some are under the misconception that the more CoQ10 they take, the healthier they will be. Perhaps you have already heard of CoQ10 being touted for heart health, vitality, and other benefits. But before you take this interesting nutrient as a supplement, learning some simple facts could help you make a more informed decision.
What is CoQ10?
CoQ10 – short for Coenzyme Q10 -- is a naturally occurring
nutrient and antioxidant found in each cell of the body. CoQ10 was first
identified by
University of Wisconsin researchers in 1957. CoQ10 has been gradually becoming
more popular in the past decade.
How Does CoQ10 work?
Each cell in the body needs a source of energy to survive, so cells break down sugars, fats, and amino acids to make energy. Small enclosures within cells that produce this energy are called mitochondria. CoQ10 exists naturally in our mitochondria and carries electrons involved in energy metabolism. CoQ10 is essential in the production of adenosine triphosphate (ATP), the basic energy molecule of each cell. Other mechanisms of action may include stabilization of calcium dependent slow channels and alteration of prostaglandin metabolism.
What Foods Contain CoQ10?
CoQ10 is found in foods,
particularly in fish and meats, and small amounts are found in nuts. There is
little or no CoQ10 in grains, vegetables or fruits. Hence, some vegetarians may
not get adequate amounts of this nutrient, although, fortunately, the body is
able to synthesize CoQ10 when dietary sources are not adequate. Dietary intake
of CoQ10 is about 2 to 5 mg per day.
Benefit
Studies with CoQ10 have mostly focused on its benefit involving certain types of cardiovascular diseases, including congestive heart failure and hypertension and to a certain extent for high cholesterol and in diabetes. Not all the results have been positive and much more research is needed before we determine the full benefits, side effects, and appropriate dosage.
Diabetes
CoQ10 may be beneficial in diabetics. It helps improve the function of endothelial cells lining blood vessels and may slightly help with blood sugar control.
Heart Attacks:
In a small trial of patients with new myocardial infarction, CoQ10 -- used in addition to aspirin and cholesterol-lowering drugs -- decreased the likelihood of further cardiac events for at least one year after the heart attack.
Heart Failure
A study in patients with heart failure showed improvement in functional status, clinical symptoms, and quality of life in end stage heart failure patients who were placed on CoQ10.
Hypertension
CoQ10 may help lower blood pressure by a small amount in some people.
Cholesterol
Individuals on cholesterol medicines of the statin class such as Lipitor, Zocor, and others, may consider taking CoQ10 supplements since statins decrease blood CoQ10 levels. Some doctors are routinely advising their patients on statin drugs to take small amounts of CoQ10.
Side Effects
High dosages of CoQ10, such as more than 100 or 200 mg, can induce restlessness, fatigue and insomnia. Long term side effects of high dose CoQ10 use are not clear at this time. I usually do not recommend more than 20 to 60 mg of CoQ10 daily on a long term basis without medical supervision.
Dosage
CoQ10 is available in a variety
of dosages ranging from 10 mg to 300 mg per capsule, but most commonly in 30,
50, and 60 mg. I personally believe that high doses are not needed, and may even
be unhelpful or detrimental. I’ve had patients who have reported fatigue when
taking dosages above 100 mg. Just as we recently discovered that high doses of
vitamin E, generally over 400 units, are not beneficial, or even potentially
harmful, we may eventually discover the same about CoQ10. I would not feel
comfortable recommending to my patients to take more than 50 mg or maximum 100
mg of CoQ10 a day, unless for the temporary treatment of a medical condition.
CoQ10 is best taken in the morning, before or with breakfast.
Summary
CoQ10 is probably beneficial in certain cardiovascular conditions and as an energy booster. Long-term therapy with 10 to 60 mg a few days a week seems a reasonable option for many individuals. Fortunately, the pace of CoQ10 research has increased over the past decade and the next few years will provide us with additional information on the best way to take advantage of this wonderful nutrient.
Q. If i am on Coumadin for a long term (many years and
the tests show it is still there) blood clot in my hip would coq10 be dangerous?
A. We are not aware of the role of CoQ10 in blood clotting or
interaction with coumadin, however this is the decision of your doctor to make.
Q. I have bought C0Q10 several times from Physician
Formulas web site. I write this e-mail because I feel confused with a newsletter
I received today, which, among other things, refers to the positive qualities of
CoQ10, but at the same time there some remarks which are caused confusion to me
as you can see from the excerpt which I copy below. Quote: And the one thing
they ALL rely on is high energy output from adequate CoQ10! CoQ10 is the single
most important nutrient you can give you body. Your very life depends on it! To
get that kind of protection, you need high-quality CoQ10 that’s easy to absorb.
But reliable CoQ10 is hard to find… You can be certain PRIMAL FORCE CoQ10 has
the highest potency of any CoQ10 available. In fact, it’s 3 TIMES more
absorbable than “ordinary” CoQ10. Here’s why… Warning: Most CoQ10 Supplements
are a Waste of Your Money! CoQ10 is so important; CoQ10 pills have sprung up
everywhere. You might think the cheapest one is the best bargain. But in
reality, they’re virtually worthless.
For starters, the cheap stuff is synthetic. It’s not real CoQ10. It’s
manufactured to look like CoQ10, but your body sees it as a “foreign substance”
and will pass it the next time you go to the bathroom. And then there’s the
“powder problem”… Most of the CoQ10 made today is in a powdered form before they
put it into that pill or capsule. (PRIMAL FORCE CoQ10 is a patented liquid gel.)
The majority of this CoQ10 is NEVER absorbed by your body. Check out this graph:
Adapted from a 2004 study by Soft Gel Technologies, Inc. My PRIMAL FORCE CoQ10
is PROVEN 3 TIMES MORE ABSORBABLE than the typical powder form. And that means 3
times more in your blood and tissues! For CoQ10 to be effective, it has to
get into your blood and stay there. Only by raising your blood levels – and
keeping them high – does CoQ10 have a chance to work its way into your organs
where it performs its miracles. If the CoQ10 you’re using is never absorbed,
it’s a complete waste! What’s worse, you’ll THINK that it’s doing something for
you… When in fact, your body is still crying out for the CoQ10 it craves! So
far, the Japanese process for making CoQ10 is the only tested, proven and
reliable way to create the CoQ10 your body can actually use. Their patented
system makes “bio-identical” CoQ10. This is exactly the same as the CoQ10 your
body makes. Only CoQ10 using this system and giving it to you in a hyper-soluble
liquid gel cap – can dramatically raise your blood levels of CoQ10. By special
arrangement, you now have a reliable source of the world’s most potent and most
bio-available CoQ10. Straight from Japan.
A. One of the first ways to spot a scam in the nutritional field is
when they claim their product is the best on the market. This type of misleading
statements have been going on in the health industry as far back as we can
remember.
Q. I read the article on Dr. Sahelian's website about
the safe amount of CoQ10 to take. I am a vegetarian and take a statin drug for
cholesterol. Physician Formulas advertises CoQ10 100 mg. For me the conflicting
statements are as follows: CoQ10 is available in a variety of dosages ranging
from 10 mg to 300 mg per capsule. I personally believe that high doses are not
needed, and may even be unhelpful or detrimental. Just as we recently discovered
that high doses of vitamin E, generally over 400 units, are not beneficial, or
even potentially harmful, we may eventually discover the same about CoQ10. I
would not feel comfortable recommending to my patients to take more than 50 mg
or maximum 100 mg of CoQ10 a day, unless for the temporary treatment of a
medical condition. The 100-mg dose of CoQ10, though, is too much since I feel
too energetic and alert even in late evening when I want to slow down and get
ready for sleep. I usually do not recommend more than 20 to 60 mg of CoQ10 on a
long-term basis without medical supervision. Q. Do you think those taking statin
drugs should take CoQ10? A. To be on the safe side, 50 mg CoQ10 can be taken a
few times a week by those on statin drugs.
So I am curious why Dr. Ray Sahelian says to take it daily and then
only a few times a week. Then other times he admits that he lays off the
supplements and herbs but not for how long. I have not done any other research
into this area other than his. My family also has a history of high blood
pressure, heart attacks, diabetes, and strokes but so far I have not had any
symptoms. I get checked regularly for the diabetes and heart conditions. With
palms folded^ Reverend, a Buddhist Monk.
A. Since there is not enough human research with CoQ10, Dr. Ray
Sahelian does not have a very strong opinion on the ideal daily CoQ10 dose. He
understands that different people need different dosages. Some do well with no
CoQ10, others may need 30 mg a day, still others 50 mg, and some patients may
temporarily benefit from 100 mg of CoQ10 or more. There are no firm guidelines,
the research with CoQ10 is not advanced enough to have a specific dosage that is
good, hence the variations and fluctuations in thinking.
Q. What is the symptoms of CoQ10 overdosing?
A. Overdosing on CoQ10 could lead to irritability, restlessness,
insomnia, nausea are potential CoQ10 toxicity side effects. Other CoQ10 side
effects are possible in the long run that we are not currently aware of.
Q. Hi -- my mum is a renal patient and has
haemodialysis 3 x week. Does COQ10 get metabolised by the kidneys or liver and
in particular, would it get dialysed out? What is the half-life of CoQ10 drug?
A. CoQ10 is not a drug but a natural substance found in the body
and in food. CoQ10 has a long half life. Those who have renal conditions may
wish to take no more than 30 mg a few times a week unless closely monitored by a
doctor. CoQ10 is metabolized in almost every cell of the body.
CoQ10: absorption, tissue uptake, metabolism and
pharmacokinetics.
Free Radic Res. 2006 May;40(5):445-53. Bhagavan HN, Chopra RK. Tishcon
Corporation, Westbury, NY 11590, USA.
Available data on the absorption, metabolism and pharmacokinetics of coenzyme
CoQ10 are reviewed. Because of its hydrophobicity and large molecular weight,
absorption of dietary CoQ10 is slow and limited. In the case of dietary
supplements, solubilized CoQ10 formulations show enhanced bioavailability. The
T(max) is around 6 h, with an elimination half-life of about 33 h. The reference
intervals for plasma CoQ10 range from 0.40 to 1.91 micromol/l in healthy adults.
With CoQ10 supplements there is reasonable correlation between increase in
plasma CoQ10 and ingested dose up to a certain point. Animal data show that
CoQ10 in large doses is taken up by all tissues including heart and brain
mitochondria. This has implications for therapeutic applications in human
diseases, and there is evidence for its beneficial effect in cardiovascular and
neurodegenerative diseases.
Q. What are the proven benefits for coq10?
A. It is difficult with herbs and supplements to use the word
"proven" since research is incomplete.
Q. Can a person take CoQ10 with Passion Rx (no Yohimbe)?
A. Both CoQ10 and Passion Rx have energizing properties, but if a
low dose is used, such as a third of Passion Rx and 30 mg or less of CoQ10, it
may be okay. Higher doses could lead to overstimulation. Passion Rx should only
be used 2 or 3 days a week.
Q. Which country is your CoQ10 made ?
A. The 30mg CoQ10 is Korean Origin. The 50mg and 100mg CoQ10 are
both from Japan.
Q. I have a friend that is so afraid to take supplements that when ever I give her a couple tablets to try, she always tells me they upset her stomach and then she admits she is afraid what they are going to do to her body. So I got her some Q10, 30mg caps and she took one for two days and then flushed the rest down the toilet as she was afraid her doctor would find out she was taking them and she would get into trouble. Then when she started feeling bad again, I told her to try a multi vitamin, she bought some but was sure after one tablet she was having heart problems from the vitamins, so I told her to ask her doctor for a prescription of which were prenatal vitamins which she took successfully and felt that they were helping her and she continues to take them! Funny how some people fear anything unless its given to them by their doctors.
Q. I bought CoQ10 of 50mg and 100mg. Since I live in
Cyprus and I had difficulty of supply I bought rather big quantities and I now
notice that the date of expiration is February 2008 and we are now Sept 2007. Do
you think I should stop taking them after this expiration date? Is it safe to
use CoQ10 and can they still be effective for some time?
A. The expiration date is an arbitrary number that is required by
law 2 years after a supplement is made, but coq10 and other nutrients are good
for years and herbs are good even longer 10 or 20 years.
Q. Can a normal healthy person start taking CoQ10 with his or her diet on regular
basis like other multi Vitamins without any harm full side effect. Other hand if
your body don't need CoQ10 but you are taking and it won't hurt your body or do
any damage.
A. There is no easy answer to this. Some people may benefit from
taking CoQ10, others may not. Much depends on a person's diet and metabolism. If
a person wants to take CoQ10, 30 mg a few times a week could offer benefits
without any foreseeable side effects.
Q. Is the use of Q10 in cases of abnormal heart rhythm
beneficial?
A. There are several types of abnormal heart rhythms, including
atrial fibrillation, premature ventricular contractions, sinus arrhythmia, etc.
Each of them may have a different cause. As a general rule, we find fish oils
and eating cold water fish to be more beneficial for abnormal heart rhythms than
CoQ10. We have not seen much studies regarding the role of CoQ10 in arrhythmia
control, but fish oils have been studied more extensively.
Q. I read with avid interest your comments on
CoQ10.This is my first time at your site and found it very interesting and
informative. I have quite an opposite reaction to CoQ10 and whatever the dose I
take, it makes me sleepy. I like the benefits though so I still take it. No
matter how alert or active I feel, once I take the 50 or 100mg dose, I sleep off
in 10mins or less. For me, it's basically a sleeping pill; but then I have to
add caffeine does not give me insomnia either. Is it me then?
A. Almost everyone notices being more energetic after taking CoQ10,
however there are individuals who have uncommon reactions to supplements and
medicines.
Q. You seem to be pretty critical of high dose CoQ10. I
took a Spectracell test that revealed I am functionally deficient in CoQ10. I do
not take statins. What is someone who is CoQ10 deficient to do in terms of
supplementation when the SpectraCell test shows a low CoQ10?
A. We are not convinced a Spectracell test is an effective way to
determine CoQ10 deficiency. If blood tests do show CoQ10 deficiency, one can
increase food intake that has CoQ10 or take a 30 mg CoQ10 supplement. It would
be best to confirm CoQ10 blood levels with another doctor and with another type
of blood test. If deficient, you can ask your doctor to read the page on CoQ10
and guide you as to proper dosage. We wish you well.
Q. I have a 90 degree curvature in my penis due to
peyronie's disease, will CoQ 10 supplement help?
A. We have not seen any research regarding the use of Co Q10
supplements for Peyronie's disease and doubt Co Q10 would be helpful.
Q. I have recently started taking a herbal blend
containing L Argenine, Damiama,
tongkat ali, Ginkgo and Ginseng. I also take a multiple,
calcium, mag and zinc fish oil and CO Q10 supplement. Is it OK to take all this
at the same time or will it be dangerous to take the COQ10 supplement at the
same time as the new herbal supplement?
A. Much depends on your overall health and the dosages of the
supplements being taken. Each person has a different response and no
generalizations can be given. It is best to first learn how each supplement is
making you feel by itself before combining.
Q. Does 100 mg CoQ10 product contain any Vitamin E or
Vitamin E equivalents? My heart doctor said recent studies have shown that
Vitamin E is bad for the heart, etc., so I stopped taking it on his advise. Is
your 100 mg CoQ10 product water soluble or only fat soluble? Apparently, if the
kind of CoQ10 is in the form that is not water soluble but only fat soluble,
then much of it will not be absorbed in the body. Perhaps in this case, one
could take a higher dosage of the fat-only soluble type to get the same affect
as taking a lower dosage water-soluble type. I take 80 mg of Lipitor daily, so
I'm depleting my CoQ10 in my body. I'll need to take a higher dosage of CoQ10 to
replace what I am depleting, especially if the type of CoQ10 is NOT water
soluble.
A. When coq10 is taken with a meal, such as breakfast, it is
absorbed quite well since there is fat in the meal. Studies with vitamin E and
heart have not been conclusive, and it is possible that very high doses may not
be heart healthy, but we are talking about more than 200 units. Most CoQ10
supplements have only a few mg of vitamin E. Our CoQ10 product does not have
vitamin E.
Q. Dr. Donsbach sells a liposomal product, vitamin C
and CoQ10 claiming it is like taking it intravenously. He also states that when
other products are taken one gets very little benefit, say 10-30% of dosage.
Liposomal yields a much higher dose from little. An ex: 1 oz. of coq 10 yields
83 mg where if one took 100 mg of a regular coq 10 they may get 10-30 mgs. Also
1 oz. of his vit c yields 1667 mgs of vit c !! Are you familiar with Liposomal ?
Is it worth the extra dollars, seems like it is if what Dr. Donsbach states is
true, though if so, it may be cheaper.
A. Taking a CoQ10 supplement with food allows it to mix with fat
and absorb well. We have not seen any evidence that taking a liposomal CoQ10 is
any healthier than taking a regular CoQ10 capsule. However, there are many
different viewpoints on this topic.
I am sensitive to doses and I have found, in the past,
that the usual market doses are too strong for me. For example, I use to take
Co-enzyme Q10 30 mg everyday but found after a few days it was too stimulating.
So I resorted to taking it every second day but I would prefer taking a smaller
dose, say 10 mg, everyday. The same thing with R Alpha Lipoic acid. I would like
trying a dose of about 5 mg to begin with but the smallest dose available is 50
mg. Can the capsule be emptied into a container with, say orange juice, and
mixed and consume a prescribed fraction of that juice each day. Or will putting
these supplements into a juice and leaving in the refrigerator for a few days
destroy the supplement? Can you give me guidance on how to lower the dosage for
both Co-enzyme Q10 and R Alpha Lipoic acid.
Yes, it is certainly okay to open a capsule of a supplement
and use a portion. I would say for most supplements it should not be a problem
to keep them a few days in juice in the refrigerator although I would prefer not
much longer. Another option is to open a capsule, pour out some of it, and then
close the capsule again. Many capsules can be opened by twisting and pulling on
each end. I encourage people who are sensitive to open capsules or break tablets
and use smaller amounts. One of the most important things to know about taking
medication or supplement pills is that there is a wide range of dosages that are
appropriate. For instance, we have had feedback from Passion Rx users that a
third of a capsule works for some people whereas others say they need a capsule
and a half or two capsules to notice an effect.
I am a 31 year old Male Aussie Expat who is currently
living in Qatar. I have been using CoQ10 for several years and currently take
200mg a day. I use the CoQ10 for arrhythmias and HOCM. I have noticed wonders in
terms of the change in my heart function, I have less episodes of arrhythmias
and feel a lot fitter and healthier.
I do notice there is a difference of CoQ10 between brands. I use one from GNC
which seems to be more effective. When I take other ones I automatically notice
a difference. There are a few side effects, I do notice mild insomnia and been a
bit restless, however compared to the side effects of beta blockers (which is
the other alternative) they are quite minimal. I get blood tests every three
months to check on things, the only change I have noticed is enzymes in my liver
seem a bit higher but not abnormal. Just wanted to give my feed back! Cheers
I am thinking of trying CoQ10 pills. Is it a good idea
to refrigerate this product so it maintains its potency.
Refrigeration is not necessary but could be slightly helpful.
Do you still recommend 10 to 30mg coq10 dosing? i am
very sensitive to everything. is it best to buy coq10 that is made in Japan for
better absorption?
Each person is different in how much CoQ10 they need, if any.
This product is absorbed well no matter where it is made.
Is it true that if a cap of COq10 is opened and it is
bright orange, it is already oxidized and will not perform the healthful effects
intended? Therefore one should take ubiquinol if one is over 25 yrs. of age.
We don't have any reason to believe it will not be effective,
and a person's age should not be a major factor in deciding which form of coq10
to take.
I am taking "Chews for Health". Dr. Friedman's
1-800-213-0512. Are they as good for you as the radio advertisements say? Also I
am thinking of ordering CoQ10 Max that I have been hearing about on the radio.
What do you know of this. The tel. no. is 1-800-727-2001. Also I am thinking of
ordering "Cal Mag" tel. no. 1-800-572-1076 for sleep and other things calcium is
good for. Would you please give me your opinion of these three supplements. I am
generally in good health. don't take any drugs and don't have health issues. I
Take supplements for prevention.
We prefer not to comment on products made by other companies.