DMG, Dimethylglycine supplement
If you find the field of mind-boosting pills, sex nutrients, and anti-aging interesting, you will certainly want to learn more about dimethylglycine, trimethylglycine, and methyl donors. Unless your major is college was chemistry, chances are you don’t remember learning about methyl donors. A methyl donor is simply any substance that can transfer a methyl group [a carbon atom attached to three hydrogen atoms (CH3)] to another substance. Methylation is a biochemical process that is essential to life, health, and regeneration of body cells. Vitamins, hormones, neurotransmitters, enzymes, nucleic acids (DNA and RNA), and antibodies depend on the transfer of methyl groups to complete their synthesis. Scientists suspect that proper methylation of DNA may prevent the expression of harmful genes, such as cancer genes. It’s quite likely that our body’s ability to methylate declines with age, contributing to the aging process, and therefore supplementation may well be beneficial. The research in this area is still very early and no firm answers are yet available. You can buy DMG here. For an excellent multivitamin.Some nutrients considered to be methyl donors include TMG. Two of the B vitamins, folic acid and B12, are also considered methyl donors.
Research with DMG supplement
Small studies have found that dimethylglycine may help boost some aspects of the
immune system. Studies using DMG for autism have generally not found it to be helpful
although there are many anecdotes of parents noticing that their autistic children
improved by taking DMG.
The Chemistry of DMG and Methyl Donors
DMG (dimethylglycine) is basically the amino acid glycine attached to two methyl
groups. DMG is a normal physiologically active nutrient found in low levels in such foods
as cereal grains, liver, and beans. Humans also naturally produce DMG in small amounts. As
a nutritional supplement, DMG acts as a building block for the synthesis of many important
substances such as
Choline Bitartrate, SAM-e, the amino acid methionine, several hormones,
neurotransmitters, and DNA.
TMG (trimethylglycine), also known as betaine, is basically the amino acid glycine attached to three methyl groups. Simply, TMG has one more methyl group than DMG.
DMG supplement emails
Q. I have a friend that thinks taking 9-12 DMG tablets at a time will help with
his migraine headaches. Watching him I see that his dizziness increases. Can he
get toxic with too much of a good thing at one time?
A. Side effects do occur with DMG and we suggest using less to
avoid dizziness or other problems.
Q. I am curious to know if you have known of anyone with positive
progressive multiple sclerosis who has had success with the use of DMG
supplement. My brother, in his 50s, was diagnosed about 6 years ago. His
mobility is declining rapidly and we are looking for anything that may slow the
progression. Someone mentioned DMG supplement to me, but I know little about it.
A. We have not seen any studies using DMG supplements for the
treatment of multiple sclerosis.
Q. Just read your article on DMG supplements. Is there an outer limit
or toxic dose / toxicity of DMG? Relative to elderly with CHF - what (mg.) range
of DMG would be recommended?
A. The best way to find out how DMG supplements will work for
anyone is to begin with a low dose, such as 100 mg, for a week and then base
future dosage on the initial response. Elderly individuals are less tolerant to
supplements and can get side effects on lower dosages.