Fibroids natural therapy

Up to 70% of women develop uterine fibroids, benign tumors that can cause pain, excessive bleeding, and infertility. Genetic studies hint that a woman's susceptibility to fibroids may be inherited from her father. Uterine leiomyomas are the most common gynecologic neoplasm in reproductive-age women. It is clear that hormonal factors play a prominent role in this disease, particularly estrogens. In addition to endogenous hormones, xenoestrogens in our environment (e.g., organochlorine pesticides, pharmacologic compounds) are of potential concern with regards to their impact on this disease. These environmental estrogens have been shown to promote the growth of leiomyoma. Fibroids are the leading reason for hysterectomies among US women, and are particularly common among African-Americans

Estrogen and fibroids
It has been suggested that unopposed estrogen may increase the risk of fibroids. Thus, any factor that reduces endogenous estrogen levels and increases progesterone levels may reduce the risk of fibroids. For example, pregnancy and oral contraceptive use decrease the risk of fibroids.

Diet and estrogen
Diet has been associated with estrogen levels. Protection against breast and endometrial cancers by vegetable and fruit intake may be mediated by isoflavonoids, which have moderate estrogenic activity and may therefore compete with other endogenous estrogens. A study of postmenopausal women showed that vegetarians had lower urinary levels of estriol and total estrogens, lower plasma prolactin levels, and higher plasma levels of sex hormone-binding globulin. Another study of premenopausal women in the United States showed that vegetarian women had 15–20% lower plasma estrogen levels than omnivores of the same age.

Diet and Fibroids research
Diet and Uterine Myomas (Fibroids).
Obstetrics & Gynecology 1999;94:395-398. Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
To analyze the relation between selected dietary indicators and the risk of uterine myomas. We used data from a case-control study on risk factors for uterine myomas conducted in Italy between 1986 and 1997. Cases included 843 women with uterine myomas whose clinical diagnoses dated back no more than 2 years. Controls were 1557 women younger than age 55 who had not had hysterectomies and were admitted for acute nongynecologic, nonhormonal, nonneoplastic conditions. Women with uterine myomas reported more frequent consumption of beef, other red meat, and ham and less frequent consumption of green vegetables, fruit, and fish. The multivariate odds ratios in the upper tertile were 1.7 (170%!) for beef and other red meat 1.4, 2.2), 1.3 for ham (1.0, 1.6), 0.5 for green vegetables (95% CI 0.4, 0.6), and 0.8 for fruit consumption (0.6, 1.0). Myoma is associated with beef and ham consumption, whereas high intake of green vegetables seems to have a protective effect.

Natural treatment for Fibroids
Exercising regularly prevents women from developing uterine fibroids. Dr. Donna Day Baird of the National Institute of Environmental Health Sciences in Research Triangle Park, North Carolina and colleagues evaluated 734 African-American women and 455 white women between 35 and 49 who belonged to a Washington, DC-based health plan. The researchers screened the women for fibroids using ultrasound and reviewed medical records to see if the women who underwent hysterectomies had a history of fibroids. The more active the women were, the less likely they were to have fibroids of any sized. Those who exercised for 7 hours or more weekly had a 40 percent lower fibroid risk than those who exercised for less than 2 hours a week. Women who reported at least 4 hours of vigorous exercise weekly were less likely to develop tumors than those who exercised less. The relationship between exercise and tumor onset was stronger than the link between exercise and tumor growth, and was seen for both black and white women. When the researchers removed women with severe fibroids that might have interfered with physical activity from their analysis, the association between exercise and lower fibroid risk remained. American Journal of Epidemiology, January 15, 2007.
   Women who exercise also have fewer fibromyalgia symptoms.

Medical therapy for Fibroids
Exogenous progestins can partially suppress estrogen stimulation of uterine fibroid growth. Danazol, an androgenic agonist, can suppress fibroid growth but has a high rate of adverse effects. GnRH agonists given by IM injection, subdermal pellet, or nasal spray are most helpful when given preoperatively to reduce fibroid and uterine volume.

Fibroids emails
Q. I am trying to reduce my uterine fibroid and will like to know if I need a prescription to purchase aromatase inhibitor. I am trying to reduce my uterine fibroids.
   A. Specific aromatase inhibitors are available by prescription.

Q. My story is very interesting and one that requires the interest and expertise of an "endocrine." I had previously gone to the gyn and I didn't have any abnormal bleeding and the gyn stated no masses and even indicated no adnexal masses. Six months later, I had surgery to the subcutaneous tissue throughout the abdominal area and I incurred major edema and trauma to the area but not to the internal organs. During the surgery, "Yes" I did have my period. And, within several days my menstrual cycle went on a cyclone such as coming and going. Within the next several months, my period began arriving sooner and lasting longer including 15 days. Shortly afterwards, I had "MULTIPLE" uterine fibroids. How odd? I knew something was wrong after the surgery because I incurred a large abdominal bulge and nobody knew until MRI revealed Multiple fibroid at all locations. Largest one is 4 cm and another one right under that one 2 cm - they are rising subserosal on top of the fundus. I won't even mention the rest and the ones inside the cavity. Presently, my uterus is enlarged to a 10 week pregnancy. But the issue is that shortly after the surgery, I incurred long periods lasting 15 days and it began arriving sooner. Now, could it be possible that my hormones went "wacky" and there was an increase in estrogen due to surgical stress, etc.... Who knows? I was 35 at that time. This is really an odd case and one that should be on medical mystery. I just do not understand how I didn't have any abnormal bleeding and I didn't have this appearance that many doctors have classified as "A Hernia" and shortly after the surgery I incurred this "Hernia" appearance which was not a Hernia but was Multiple Intramural fibroid which protrude into the abdomen area. What is the real reason for uterine fibroids? Could it also be possible that a fluctuations in hormones such as "estrogen" due to a previous surgical stress promote the growth of fibroid? Very interesting.
   A. Yes, estrogen is involved in fibroid growth.

Q. I am presently researching one of the ingredients in Fibrovan, Komodo Pharmac. in Indianapolis, IN for the purpose of dissolving huge uterine fibroids. i would appreciate any information you could provide me. I would like to dissolve these huge fibroids of course without surgery or the procedure U.A.E. those are not my options. I forwarded this my family dr. who has not responded back to me. I am not on any medications. Do you know if Fibrovan is safe and or works in shrinkage?
   A. We are not familiar with Fibrovan research, but a look at the website indicates it has nattokinase, EGCG and lycopene. As of January of 2008, we are not seen any human studies with Fibrovan and the treatment of fibroids.

Q. Can ladies take nattokinase to shrink their fibroids ?
  A. We have not seen any research regarding the use of nattokinase for fibroids in women.

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