Folic Acid Food source - Foods High in Folic Acid
Folic acid–containing supplements have become popular, especially for
women who are ready to become pregnant. Folic acid fortified foods,
including enriched cereal–grain products and ready-to-eat cereals, are the
primary food sources of folic acid intake in the United States.
Other food sources rich in folic acid are green leafy vegetables and liver.
There are thousands of food products, including such widely used products
as flour and pasta, that contain folic acid enriched cereal-grain
components.
Folic acid is a synthetic compound of folate, a B
vitamin. You can find a
Vitamin-B-Coenzyme supplement here.
Function of folic acid
Folic acid
generally functions in cooperation with vitamin
B12 in many metabolic reactions, including the synthesis of DNA. Folic acid helps reduce
levels of homocysteine.
Folic acid functions as a methyl donor. Folic acid is
found in almost all foods and the recommended daily intake is about 400 micrograms. The
coenzyme form of folate is called tetrahydrofolate. A shortage of folic acid can
lead to anemia.
FDA allows these two qualified health claims for
Folic Acid:
A. Healthful diets with adequate folic acid may reduce a woman's risk
of having a child with a brain or spinal cord defect. The Institute of
Medicine of the National Academy of Sciences recommends that women capable
of becoming pregnant consume 400 micrograms of folic aced daily from
supplements, folic acid fortified foods, or both, in addition to consuming food folate from a varied diet."
B. 0.8 mg folic acid in a dietary supplement is more effective in reducing
the risk of neural tube defects than a lower amount in foods in common
form. FDA does not endorse this claim. Public health authorities recommend
that women consume 0.4 mg folic acid daily from folic acid fortified foods or dietary
supplements or both to reduce the risk of neural tube defects."
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Folic Acid benefit
Folic acid is a nutrient essential for the health and function of DNA. Relative
deficiency of folic acid may occur in pregnancy and hyperproliferative or
chronic inflammatory disorders. Folic acid supplementation could prevent neural
tube defects and in limiting side effects methotrexate. Supplements of folic
acid may reduce the risk of colon cancer and perhaps cognitive decline. Folate
is one of the vitamins that lower blood levels of homocysteine, which in turn is
a thought to be a risk factor for cardiovascular diseases. Folic acid
supplementation may be helpful in those who have chronic inflammatory skin
diseases, such as moderate to severe psoriasis. For the time being, a daily
supplement of 400 micrograms appears to be sufficient.
high doses of folic acid, whether from supplements or food sources,
improve endothelial function, which could potentially reduce the risk of
cardiovascular disease.
Folic Acid Food Sources
You can get folic acid in beans and legumes; citrus fruits and juices;
wheat bran and other whole grains; dark green leafy vegetables; and poultry,
pork, shellfish, and liver.
Benefits of folic acid
- Homocysteine
Folic acid reduces plasma homocysteine and may be an important therapy
for preventing cardiovascular disease. A key mechanism in the benefit of folic
acid in heart disease may be the reduction of
arterial stiffness. Folic acid is a safe and effective supplement that targets large artery
stiffness and may prevent isolated systolic hypertension.
Folic acid and Osteoporosis
Folic and other B vitamins seem even more of a wonder drug than anyone
suspected: Already known to prevent severe birth defects and heart attacks, they
may also reduce the risk of osteoporosis.
Folic acid and Cognitive Decline
High-dose folic acid pills might help slow the cognitive decline of aging. So says a Dutch
study that's the first to show a vitamin could really improve memory.
The research adds to
mounting evidence that a diet higher in folic acid is important for a variety of
health effects. It's already proven to reduce birth defects, and research
suggests it helps ward off heart disease and strokes, too.
But as people age, some decline in memory and other brain functions is
inevitable. Taking 800 micrograms of folic acid a day slowed that brain drain,
reported lead researcher Jane Durga of Wageningen University in the Netherlands.
In the study, 818 cognitively healthy people ages 50 to 75 swallowed either
folic acid or a dummy pill for three years.
On memory tests, the supplement users had scores comparable to people 5.5 years
younger, Durga said. On tests of cognitive speed, the folic acid helped users
perform as well as people 1.9 years younger.
That's significant brain protection, with a supplement that's already well-known
to be safe.
Folic Acid and Colon Cancer
A suboptimal intake of folic acid may play a role in the development of colorectal cancer, which points to a possible role for folic acid supplementation in colorectal cancer prevention. In individuals with colorectal adenomas -- polyps that can be precursors to bowel cancer -- folic acid supplementation reverses so-called DNA hypomethylation.
Folic Acid and Stroke
After folic acid fortification of enriched grain products was fully
implemented in 1998, deaths due to strokes dropped rapidly in the US and Canada.
The main reason for folic acid fortification was to reduce the number of babies
born with neural tube defects such as spina bifida. There is "accumulating,
controversial evidence" that homocysteine -- an amino acid in the blood -- is a
risk factor for stroke and heart disease, Dr. Quanhe Yang, from the Centers for
Disease Control and Prevention in Atlanta, said in a statement. Folate decreases
homocysteine levels, which may help explain the drop in stroke deaths. Yang's
team compared stroke mortality trends between 1990 and 2002 in the US and Canada
with those in England and Wales, where folate fortification is not required.
Stroke mortality was already falling in the US and Canada from 1990 to 1997, but
in 1998 a precipitous drop began, the report indicates. In the US, the annual
decrease in mortality during the earlier period was 0.3 percent, whereas
starting in 1998 the reduction was 2.9 percent. Similar results were seen in
Canada. By contrast, stroke mortality rates did not decline significantly in
England and Wales between 1990 and 2002. Source: Circulation, March 14, 2006.
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