Hawthorn Supplement Facts:
Serving Size: 3 Capsules
Servings Per Container: 60

Amount per Serving
Hawthorn (berry)  1,530 mg


You can buy Hawthorn supplement here.

What's in Hawthorn supplement?
Hawthorn contains flavonoids, procyanidins, and other active compounds.

How does Hawthorn supplement work?
Hawthorn acts as a vasodilator, increasing blood supply to the heart and improving circulation to the extremities by decreasing arterial resistance. Hawthorn also has positive inotropic and beta-blocking effects, along with antioxidant and anti-inflammatory benefits. CoQ10 is a supplement that helps cardiac function. for more CoQ10 or Coenzyme Q10 information.

Hawthorn extract useful in heart failure
An extract from the leaves of hawthorn tree, available in Europe, extended the lives of patients with congestive heart failure, who were already receiving medical treatment, by an average of 4 months. Results of the 2,681-patient clinical trial that tested the extract known as WS 1442 against a placebo, were done by Dr. Christian Holubarsh, lead investigator of the study that was sponsored by the Germany-based Dr. Willmar Schwabe Group. The extract from the hawthorn tree, which has its origins in Europe and Ireland and grows throughout North America, is a natural antioxidant that has been used in parts of Europe to treat heart failure, a condition in which the heart is no longer able to pump enough blood to the body's other organs. Patients in the trial had severely impaired left ventricular function, indicating advanced congestive heart failure. The primary goal of the study was time to first cardiac event, defined as sudden cardiac death, death due to progressive heart failure, fatal and nonfatal heart attacks or hospitalization due to heart failure. Researchers found that patients who received the extract had a 20 percent reduction in cardiac-related deaths, which translated into four months of added survival time during the first 18 months of the study. They said the lower number of deaths in the WS 1442 group compared with those who received placebo on top of their regular medicines was an indication of the safety of the hawthorn extract.

What form of Hawthorn extract is best?
The methanol or alcohol extract of hawthorn seems to be more effective.

What is the dosage of Hawthorn?
The recommended daily dose of hawthorn is 160-900 mg of a native water-ethanol extract of the leaves or flowers (equivalent to 30-169 mg of epicatechin or 3.5-19.8 mg of flavonoids) administered in two or three doses.

What about Hawthorn side effects?
At therapeutic dosages, hawthorn may cause a mild rash, headache, sweating, dizziness, palpitations, sleepiness, agitation, and gastrointestinal symptoms.

Interactions with drugs
Hawthorn may interact with vasodilating medications and may potentiate or inhibit the actions of drugs used for heart failure, hypertension, angina, and arrhythmias.

Nature's Way Hawthorn Berries, 510 mg
Hawthorn (Crataegus oxyacantha) berries of this European species have been used since ancient times for well-being and as a cardiovascular tonic.

Recommendation: Take 1 or 2 capsules 1 or 3  times daily, preferably with food, and as recommended by your doctor. Supplement Facts Hawthorn (berry) 1.53 g (1,530 mg)

Hawthorn Research Update
A randomised double blind placebo controlled clinical trial of a standardized extract of fresh Crataegus berries (hawthorn) in the treatment of patients with congestive heart failure NYHA II.
Degenring FH. Bioforce AG, Roggwil, Switzerland.
Phytomedicine. 2003;10(5):363-9.
A placebo controlled, randomised, parallel group, multicentre trial conducted shows the efficacy and safety of a standardised extract of fresh berries of hawthorn in patients with cardiac failure NYHA class II. A total of 143 patients (72 men, 71 women, mean age of 64.8 (8.0 years) were recruited and treated with 3 times 30 drops of the hawthorn extract (n = 69) or placebo (n = 74) for 8 weeks. The primary variable for the evaluation of efficacy was the change in exercise tolerance determined with bicycle exercise testing, secondary variables included the blood pressure-heart rate product (BHP). Subjective cardiac symptoms at rest and at higher levels of exertion were assessed by the patient on a categorical rating scale. An overall assessment of efficacy at the final visit was provided by the patient and the investigator. In the ITT population there was a significant increase in exercise tolerance in both groups between visit 1 and visit 3. The difference between the treatment groups was 8.3 watts in favour of the standardised extract of fresh hawthorn. The result is confirmed in the PP population. Changes in BHP at 50 watts and at comparable maximum load were in favor of hawthorn extract but the results are not statistically significant. The subjective assessment of cardiac symptoms at rest and at higher levels of exertion did not change significantly and the patient and investigator overall assessment of efficacy were similar for the two groups. Hawthorn was well tolerated and had a high level of patient acceptability. The significant improvement, due to the fact that dyspnoea and fatigue do not occur until a significantly higher wattage has been reached in the bicycle exercise testing allows the conclusion that the recruited NYHA II patients may expect an improvement in their heart failure condition under long term therapy with the standardised extract of fresh hawthorn berries.

Investigation of the pharmaceutical and pharmacological equivalence of different Hawthorn extracts.
Phytomedicine 2003 Jan;10(1):8-16
Vierling W, Universitat Munchen, Germany
Seven Hawthorn extracts were tested in isolated guinea pig aorta rings. The effect on noradrenaline- (10 microM) induced contraction was investigated. The extracts were prepared using ethanol (40 to 70% v/v), methanol (40 to 70% v/v), and water as the extraction solvents. The aqueous-alcoholic extracts displayed similar spectra of constituents. They were characterised by similar procyanidin, flavonoid, total vitexin and total phenols content and by similar TLC fingerprint chromatograms. The aqueous extract, however, showed a different fingerprint and a noticeably lower concentration of procyanidins, flavonoids and total phenols but a similar total vitexin content. All 7 extracts had a relaxant effect on the aorta precontracted by noradrenaline and led to relaxations to 44 until 29% of the initial values. The EC50 values of the aqueous-alcoholic extracts varied between 4.16 and 9.8 mg/l. The results show that Hawthorn extracts with comparable quality profiles were obtained by using aqueous-alcoholic extraction solvents (40 to 70% ethanol or methanol). The hawthorn extracts exerted comparable pharmacological effects. When using water as the extraction solvent, both, the spectrum of constituents and the pharmacological effect, deviated remarkably. It is thus possible to obtain bioequivalent extracts with comparable effect profiles by using 40 to 70% ethanol or methanol as the extraction solvent.

Hawthorn: pharmacology and therapeutic uses.
Am J Health Syst Pharm 2002 Mar 1;59(5):417-22
Rigelsky JM, Sweet BV.
Hawthorn (Crataegus oxyacantha) is a fruit-bearing shrub with a long history as a medicinal substance. Hawthorn uses have included the treatment of digestive ailments, dyspnea, kidney stones, and cardiovascular disorders. Today, hawthorn is used primarily for various cardiovascular conditions. The cardiovascular effects are believed to be the result of positive inotropic activity, ability to increase the integrity of the blood vessel wall and improve coronary blood flow, and positive effects on oxygen utilization. Flavonoids are postulated to account for these effects. Hawthorn has shown promise in the treatment of New York Heart Association functional class II congestive heart failure (CHF) in both uncontrolled and controlled clinical trials. There are also suggestions of a beneficial effect on blood lipids. Trials to establish an anti-arrhythmic effect in humans have not been conducted. The recommended daily dose of hawthorn is 160-900 mg of a native water-ethanol extract of the leaves or flowers (equivalent to 30-169 mg of epicatechin or 3.5-19.8 mg of flavonoids) administered in two or three doses. At therapeutic dosages, hawthorn may cause a mild rash, headache, sweating, dizziness, palpitations, sleepiness, agitation, and gastrointestinal symptoms. Hawthorn may interact with vasodilating medications and may potentiate or inhibit the actions of drugs used for heart failure, hypertension, angina, and arrhythmias. The limited data about hawthorn suggest that it may be useful in the treatment of NYHA functional class II CHF.

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Hawthorn supplement questions
Q. Could you please, tell me if a hawthorn supplement has side effects for Grave's disease remission person?
   A. We searched Medline in May 2008 and could not find any studies regarding the influence of hawthorn berries on Grave's disease.