HOPS
supplement
Hops oil sleep beer hops research hops
herb hops anxiety
Hops is useful as a sleep inducer, has antioxidant activity, estrogen-like
properties, and potential anti-tumor activity. Furthermore, compounds in hops
reduce insulin resistance. For more
hops information.
Nature's Way Hops Flowers, 310 mg
Good Night Rx with hops plant extract for deeper sleep, formulated by Ray
Sahelian, M.D.
Hops
Supplement Facts:
Hops (flower)
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Hops and valerian
together for sleep
Valerian and hops are traditionally used as sleep-inducing herbs. When the
chemical adenosine is released in the frontal basal cortex, sleep is induced.
Valerian has an adenosine like action and supports the readiness to fall asleep.
The control of the sleep-wake rhythm induces sleep when the time-related
interaction is operating properly. The control is closely related to melatonin
secretion. Hops act in a similar way to melatonin. Therefore there is benefit of
a valerian and hops combination in inducing sleep.
Hops and Cancer
Extracts of several estrogenic herbs, including hops,
black cohosh and vitex,
inhibited growth of breast cancer cells. These in vitro results suggest that certain herbs
and phytoestrogens may have potential in the prevention of breast cancer.
Six flavonoids from hops (Humulus lupulus) were tested for their antiproliferative
activity in human breast cancer (MCF-7), colon cancer (HT-29) and ovarian cancer. All the
hop flavonoids were cytotoxic in the three cell lines. As antiproliferative agents,
chalcone and its (flavanone isomer may have potential chemopreventive activity against
breast and ovarian cancer in humans.
Hops phytoestrogen
A potent phytoestrogen in hops, 8-prenylnaringenin, has an activity greater than other
established plant estrogens. The estrogenic activity of this compound was reflected in its
relative binding affinity to estrogen receptors from rat uteri. The presence of
8-prenylnaringenin in hops may provide an explanation for the accounts of menstrual
disturbances in female hop workers. This phytoestrogen can also be detected in beer, but
the levels are low and should not pose any cause for concern.
Hope as
anti-inflammatory
Metagenics, Inc., a developer and manufacturer of medical foods and
nutraceuticals sold through healthcare practitioners, announced the publication
of a scientific paper, “Safety, efficacy and anti-inflammatory activity of rho
iso-alpha-acids from hops,” in the May 2008 issue of Phytochemistry, the
International Journal of Plant Chemistry, Plant Biochemistry and Molecular
Biology.
Previous work by the Metagenics MetaProteomics nutrigenomics research center had
identified a defined mixture of rho iso-alpha-acids (RIAA), a derivative of hops
(Humulus lupulus L.), as a selective COX-2 inhibitor. The Phytochemistry paper
summarizes the results of several new studies conducted by Metagenics evaluating
the efficacy and safety of RIAA. Among the findings:
Clinically, the hops extract rho iso-alpha-acids mixture produced a
reduction in WOMAC Global scores (a standard measurement used to assess the
symptoms of pain, stiffness and physical function), in patients exhibiting knee
osteoarthritis.
Rho iso-alpha-acids was shown to selectively inhibit the inducible
(inflammatory) activity of COX-2 without affecting constitutive (housekeeping)
COX-2 activity.
According to Jeffrey S. Bland, PhD, Metagenics Chief Science
Officer and President of MetaProteomics, “Based on our cumulative research, RIAA
appears to have the potential to serve as a safe and efficacious option in some
areas where specific COX-2 inhibitors have been traditionally used. We’re
excited about the possibilities in helping millions of people who are looking
for safer approaches for pain relief.”
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