Alpha lipoic acid, also known as "lipoic acid" is a powerful, natural antioxidant slowly becoming recognized as having some unique properties in the therapy and prevention of a broad range of diseases. In addition to being a powerful antioxidant, alpha lipoic acid helps the body use glucose, hence alpha lipoic acid's potential role in improving blood sugar control. Alpha lipoic acid reduces complications from a high sugar diet. Lipoic acid is readily absorbed from the diet or as a supplement. Lipoic Acid has a variety of benefits, particularly for diabetics.

R Alpha Lipoic Acid supplement

R-Alpha Lipoic Acid. R-ALA is much more potent (2 times on average) than commonly sold synthetic lipoic acid which contains both the R and S forms of lipoic acid. The S form is chemically the mirror image of the R form of lipoic acid and is not useful to the body.

R Alpha Lipoic Acid Supplement Facts
R Alpha Lipoic Acid - 50 mg *

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Conditions where alpha lipoic acid supplement may be helpful
Research in humans with alph lipoic acid is still incomplete. However, lipoic acid may theoretically be useful in a variety of medical conditions, including diabetes, heart disease, hypertension, high cholesterol, Alzheimer's disease, and Huntington's disease.

Alpha Lipoic Acid as an Antioxidant
Lipoic acid can regenerate vitamin C from its oxidized form, dehydroascorbic acid. Lipoic acid can also potentially regenerate other antioxidants. Lipoic acid increases the levels of glutathione, a very important antioxidant normally found in our cells and responsible for mopping up all types of toxins and free radicals. Glutathione supplements, however, are not helpful since glutathione does not have the ability to cross cell membranes. Fortunately, both laboratory and animal studies have shown that lipoic acid can stimulate the production of this antioxidant. This is particularly important during periods of excessive stress or exposure to radiation or toxic substances. Lipoic acid also acts as a powerful antioxidant in the brain and is likely to protect brain cells from toxins.

Alpha lipoic acid supplement protects blood vessel lining from high blood sugar damage
The antioxidant alpha-lipoic acid improves endothelial dysfunction induced by acute hyperglycaemia during OGTT in impaired glucose tolerance.
Clin Endocrinol (Oxf). 2007 December. Department of Endocrinology, Wuhan General Hospital of Guangzhou Command, Wuhan, Hubei Province, P. R. China.
Impaired glucose tolerance (IGT) is considered a transitional phase in the development of type 2 diabetes, and is also independently associated with the occurrence of cardiovascular disease. Endothelial dysfunction represents a very early step in the development of atherosclerosis. The aim of the present study was to examine endothelial dysfunction in the fasting state and after a glucose challenge as well as after administration of alpha lipoic acid. The study subjects included 42 IGT patients and 26 healthy individuals (control group). The IGT patients were randomly divided into two groups, 21 in each group (the alpha-lipoic acid group and the placebo group). In the alpha-lipoic acid group, 300 mg of alpha-lipoic acid was administrated before an oral glucose tolerance test. In subjects with IGT, endothelium-dependent arterial dilation was impaired both in the fasting state and after a glucose challenge, probably through increased production of oxygen-derived free radicals. The endothelial dysfunction observed after a glucose challenge is related to the extent of hyperglycaemia and TBARS, and an antioxidant agent such as alpha lipoic acid can improve the impairment of endothelial function induced by acute high blood sugar.

Alpha Lipoic Acid supplement side effects
There are no indications that low doses of lipoic acid, such as 5 to 20 mg, have side effects. Higher doses could cause nausea or stomach upset, along with over-stimulation, fatigue, and insomnia. High doses could also potentially lower blood sugar. This is often beneficial to patients who have diabetes, but it requires close monitoring of blood sugar levels. Unlike most antioxidants such as vitamins C, E, and selenium, there is actually a noticeable effect from taking alpha lipoic acid. Some people notice enhanced visual acuity. Higher dosages, such as 50 mg or more, even when taken in the morning, can cause shallow sleep.

Lipoic acid helpful in Diabetic Neuropathy
High blood sugar levels for prolonged periods can be toxic to nerves in the body. Diabetics who don't control their blood sugar eventually start losing sensation in their feet. Other problems follow resulting from damage to various nerves that supply internal organs. Even impotence can result due to loss of nerve sensation in genital organs. However high blood sugar may not be the only culprit. Diabetics are usually under high oxidative stress and this probably contributes to their neurological problems.
   Several studies indicate that alpha lipoic acid has beneficial effects on diabetic neuropathy, party due to its actions as an antioxidant, and also by improving the circulation to tiny blood vessels supplying nerve tissue. For a natural sugar alternative, see stevia benefit information.

Alpha Lipoic Acid and Memory
Feeding alpha lipoic acid and acetyl-l-carnitine to old rats improves performance on memory tasks by lowering oxidative damage and improving mitochondrial function.

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Alpha lipoic acid supplement questions
Q. Dr. Sahelian recommends that people take 5, 10 or up to 50 mg of R alpha lipoic acid daily, but I see many companies offering it only in 50 mg capsules.
   A. A capsule can be opened and the partial contents used, the rest stored for another day.