Royal
jelly allergy
Caution: certain individuals may have allergic reactions to royal jelly.
Composition of royal jelly
Royal Jelly is a milk like secretion made by worker bees in the hive.
It is so named because it serves as the sole food for the queen bee. It supplies
B-vitamins, vitamins A, C, D, E & K, more than a dozen key minerals. amino acids, and other important constituents, including nucleic acids (DNA and
RNA).
Up to 50% (dry mass) of royal jelly is protein.
Health benefit of royal
jelly
Royal jelly has potential health benefits such as antitumor, antibacterial,
cholesterol lowering, antiinflammatory, and immune influencing properties. Royal
jelly is beginning to be studied as a supplement that can influence the health
of patients with Graves' disease. Royal jelly, as a whole or some of its
individual components, stimulates production of type I collagen and other
activities for bone formation through action on osteoblasts.
Royal jelly and osteoporosis
Royal jelly has been used worldwide for many years as medical products, health
foods and cosmetics. Royal jelly contains testosterone and has steroid
hormone-type activities and has been found in rodent studies to improve bone
strength.
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Royal jelly antifungal activity
Efficacy of royal jelly
against the oxidative stress of fumonisin in rats.
Toxicon. 2007 Aug;50(2):256-69. Food Toxicology and Contaminants
Department, National Research Center, Dokki, Cairo, Egypt.
Fumonisins are mycotoxins produced by Fusarium verticillioides, frequently
associated with corn. It produces toxicity, including teratogenicity, equine
leukoencephalomalacia, porcine pulmonary edema, hepatic or renal damage in most
animal species and perturb sphingolipid metabolism. The aim of the present study
was to evaluate the protective effects of royal jelly against fumonisins
toxicity. Sixty male Sprague-Dawley rats were divided into six treatment groups
including the control group; group fed fumonisins -contaminated diet (200mg/kg
diet) and the groups treated orally with royal jelly (100 or 150mg/kg body
weight) with or without fumonisins for 3 weeks. It could be concluded that royal
jelly have a protective effects against fumonisins toxicity and this protection
was dose dependent.
Royal jelly and the immune
system
Fatty acids from royal jelly have an influence on the immune system. How this
influences health and disease in humans remains to be evaluated.
Fatty acids isolated from royal jelly modulate
dendritic cell-mediated immune response in vitro.
Int Immunopharmacol. 2007 Sep;7(9):1211-20. Institute of Medical
Research, MMA, Belgrade, Crnotravska 17, 11002 Belgrade, Serbia.
Researchers in Belgrade, Serbia, studied the effect of 10-hydroxy-2-decanoic
acid (10-HDA) and 3,10-dihydroxy-decanoic acid (3,10-DDA), isolated from royal
jelly, on the immune response using a model of rat dendritic cell (DC)-T-cell
cocultures. Both fatty acids, at higher concentrations, inhibited the
proliferation of allogeneic T cells. The effect of 10-HDA was stronger and was
followed by a decrease in interleukin-2 (IL-2) production and down-regulation of
IL-2 receptor expression. Spleen DC, cultivated with 10 microg/ml of fatty acids
down-regulated the expression of CD86 and the production of IL-12, but
up-regulated the production of IL-10. In contrast, DC, pretreated with 100
microg/ml of 3,10-DDA, up-regulated the expression of CD86 and augmented the
proliferation of allogeneic T cells. The highest dose (200 microg/ml) of both
fatty acids which was non-apoptotic for both T cells and DC, down-regulated the
expression of MHC class II and CD86, decreased the production of IL-12 and made
these DC less allostimulatory. The immunosuppressive activity of 3,10-DDA was
also confirmed in vivo, using a model of Keyhole lymphet hemocyanine
immunization of rats. In conclusion, our results showed the immunomodulatory
activity of royal jelly fatty acids and suggest that DC are a significant target
of their action.
Royal jelly supplement emails
Q. if I have asthma when young but recovered, can I take royal jelly supplement?
A. Asthma has many causes. Each person is different. A few people
have an allergy to royal jelly but most people do not. We cannot advise you to
take or not to take a royal jelly supplement, but you doctor may wish to read
the info on this topic and guide you.
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