Tribulus Terrestris product benefit and side effects

Tribulus terrestris is a plant long used around the world for the treatment of various ailments. Tribulus terrestris is popularly claimed to improve sexual function in humans. In Turkey, tribulus is commonly used in folk medicine for the treatment of abdominal colic, hypertension and high cholesterol. In Europe tribulus terrestris has been used in folk medicine throughout history, as far back as the Greeks, treating such wide-ranging conditions as headache, nervous disorders, constipation, and sexual dysfunction. In China and India, tribulus has been touted for use in liver, kidney, urinary, and cardiovascular remedies. Additional sexual herbs and supplements include Maca herb,  Horny-Goat-Weed herbal extract and Deer-Antler-Velvet. Side effects include insomnia and feeling hot.

Tribulus Terrestris product
Tribulus terrestris is a tropical vine common in sandy soil throughout India, Pakistan, and Sri Lanka. Tribulus contains furostanol saponins, the active component. This herb is popular for its potent role in supporting reproductive function. Tribulus terrestris can be used by both men and women.

Tribulus Terrestris Supplement Facts
Tribulus Terrestris -- 400 mg
     (standardized to 40 % saponins)

Click here to buy Tribulus Terrestris product

Sexual herbs and supplements that are effective in improving stamina and performance
Additional sexual herbs that have an influence on sexuality include: Ashwagandha herb, avena sativa, butea superba, Catuaba herb, cnidium monnieri, coleus forskohlii, damiana, Deer-Antler-Velvet extract, fish oils, Horny-Goat-Weed herb, Maca herb, Mucuna-Pruriens herb
, Muira-Puama herb, Rhodiola herb, Tongkat-Ali herb, and Yohimbe.

Tribulus terrestris dosage
Q. I've got a question regarding the dosage on tribulus terrestris sex pill product. What is the right tribulus terrestris dosage for long term use?
   A. The dosage of tribulus terrestris can vary between individuals and at different times. The idea is to use it the least amount and dosage that works. This could be as little as once or twice a week but no more than 4 times a week. Tribulus terrestris dosage also depends on what other supplements or medications a person is taking.

Tribulus terrestris and hypertension
Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity.
Life Sci. 2003 Oct 24;73(23):2963-71. Department of Pharmacology, Razi Institute for Drug Research and Cellular and Molecular Research Center, School of Medicine, Iran University of Medical Sciences, PO Box 14155-6183 Tehran, Iran.
Tribulus terrestris is a natural herb used for treating many diseases including hypertension. According to previous reports, aqueous extract of tribulus fruits may have some antihypertensive effect with an unknown mechanism. The present study investigated the antihypertensive mechanism of tribulus in 2K1C hypertensive rats by measurement of circulatory and local ACE activity in aorta, heart, kidney and lung.  The ACE activity in all tissues of 2K1C rats including: aorta, heart, kidney, lung as well as serum were significantly increased compared to normal rats. The ACE activity in all tissues of tribulus fed hypertensive rats was significantly lower than that of hypertensive rats, which was more pronounced in kidney. These results indicated that there is a negative correlation between consumption of tribulus terrestris and ACE activity in serum and different tissues in 2K1C rats.

Tribulus and Blood Sugar
[Hypoglycemic effect of saponin from Tribulus terrestris]
Zhong Yao Cai. 2002 Jun;25(6):420-2. School of Life Science, East China Normal University, Shanghai 200062.
To study the hypoglycemic effect of saponin from Tribulus terrestris L. Alloxan was used to establish the diabetic model in mice. Phenformin Hydrochlride Tables was used as the positive control. The level of glucose, triglyceride, cholesterol and SOD in serum were determined. The level of serum glucose could be significantly reduced by saponin from Tribulus terrestris, which was the rate of 26.25% and 40.67% in normal mice and diabetic mice in respectively. The level of serum triglyceride could be reduced 23.35%. The saporin could also decrease the content of serum cholesterol. Serum SOD activity of the mice was increased by the saponin. CONCLUSION: Saponin from Tribulue terrestris could significantly reduce the level of serum glucose.

Source Naturals Tribulus, 750 mg, 60 Tablets
Tribulus terrestris is a tropical vine common in sandy soil throughout India, Pakistan, and Sri Lanka. Source Naturals Tribulus contains over 40% frustanol saponins, the active component. This south Asian herb is popular for its potent role in supporting reproductive function. Tribulus terrestris can be used by both men and women.

Tribulus Terrestris 750 mg (minimum 40% frustanol saponins)

Tribulus Terrestris questions
Q. I am very interested in tribulus terrestris. Could you please tell me any drug interaction with Synthroid (for hypothyroid) Effexor xr (depression & anxiety.
   A. There have not been any studies regarding the combination of tribulus terrestris and Synthroid or Effexor. Small amounts of tribulus terrestris could be fine, but higher amounts could cause side effects. If you plan to use tribulus terrestris, start with a quarter of a capsule.

Q. I have enjoyed reading Natural Sex Boosters, and have been researching aphrodesiac herbs on the internet as well. I am unable to find evidence for a stimulating effect on testosterone (or on LH ) attributable to tribulus terrestris Is there any supplement that will enhance the conversion of androstenedione (endogenous) to testosterone ?
   A. We have not seen enough human research on tribulus terrestris or other aphrodisiac herbs to know what the short term and long term effects are on testosterone secretion or production.

Q. I came across your website when looking for more information on Tribulus Terrestris. This is because an extract of this plant is being promoted for 'stimulating the Hypothalamus'. As I suffer from Narcolepsy, for which the Hypothalamus is responsible, I wondered if Tribulus Terrestris might help? I certainly don't need an aphrodisiac and don't know what effect an increase in testosterone would have on me. Should I give Tribulus Terrestris a try to see what effect it has on my narcolepsy? What should I look for in a product in terms of ingredients?
   A. There are countless herbs that influence alertness and could keep a person awake, tribulus terrestris is not the only one. Ginseng, ginkgo, acetylcarnitine, dmae, products such as Mind Power Rx and Eyesight Rx all help alertness. It is difficult to predict which one or combinations will help any individual person. We have not seen any specific studies in humans regarding tribulus terrestris and narcolepsy or the long term influence of this herb on the hypothalamic hormones.

Effect of Tribulus terrestris on nicotinamide adenine dinucleotide phosphate-diaphorase activity and androgen receptors in rat brain.
J Ethnopharmacol. 2005 Jan 4;96(1-2):127-32. Department of Obstetrics and Gynaecology, National University Hospital, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074, Singapore.
Tribulus terrestris L. (Zygophyllaceae) have been used as an aphrodisiac both in the Indian and Chinese traditional systems of medicine. Administration of Tribulus terrestris extract increased sexual behaviour and intracavernous pressure both in normal and castrated rats and these effects were probably due to the androgen increasing property of tribulus terrestris. The objective of the present study is to evaluate the effect of Tribulus terrestrison nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) activity and androgen receptor (AR) immunoreactivity in rat brain. There was an increase in both NADPH-d (67%) and AR immunoreactivity (58%) in Tribulus terrestris treated group and these results were statistically significant compared to the control. Chronic treatment of Tribulus terrestris in rats increases the NADPH-d positive neurons and AR immunoreactivity in the PVN region. Androgens are known to increase both AR and NADPH-d positive neurons either directly or by its conversion to oestrogen. The mechanism for the observed increase in AR and NADPH-d positive neurons in the present study is probably due to the androgen increasing property of tribulus terrestris. The findings from the present study add further support to the aphrodisiac claims of tribulus terrestris.

Q.  I have a question about tribulus terrestris product. I have read some studies that have shown many of these tribulus products only produce a placebo effect unless they are made from the leaf of the Tribulus terrestris plant. One study suggested that using 1500 mg/day, proved to be successful for many functions. Could you tell me about the tribulus terrestris product on your site and if it meets this criteria?
   A. The tribulus terrestris product by Physician Formulas is an extract of 40 percent saponins. It is potent. One capsule is just right for most people and it may be a little too potent for those who are sensitive to herbs. We don't suggest taking more than one capsule.

Q. Can tribulus terrestris lead to better ejaculations?
   A. Yes, some people notice better ejaculations with tribulus, although tongkat ali works quite well, too.

Q. I have just recently started taking tribulus terrestris product 500 mg 2 times a day in the form of Tribex Gold 50-I am cycling 5 days on-two days off. I have had erectile dysfunction fro about a year, with high blood pressure, which is now normal with meds. Would it hurt to add Passion RX to my regime? I am desperate to return to full erections.
   A. We don't suggest using Passion Rx the same day as tribulus terrestris.


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