Trimethylglycine
pill Health benefit of Trimethylglyine supplement
Trimethylglycine TMG (also known as betaine), and Dimethylglycine DMG, are methyl donors that help in the production of several brain chemicals and hence improve mood, energy, wellbeing, alertness, concentration, and visual clarity.
Unless your major is college was chemistry, chances are you don’t remember learning about methyl donors. But if you find the field of mind boosting interesting, you will certainly want to learn more about these supplements. A methyl donor is simply any substance that can transfer a methyl group [a carbon atom attached to three hydrogen atoms (CH3)] to another substance. Many important biochemical processes rely on methylation, including the metabolism of lipids and DNA. Scientists suspect that adequate methylation of DNA can prevent the expression of harmful genes, such as cancer genes. It’s quite likely that our body’s ability to methylate declines with age, potentially contributing to the aging process, and therefore supplementation is an interesting idea in terms of health benefits.
Research update
Trimethylglycine lowers homocysteine levels.
Trimethylglycine has been found to protect liver cells from toxins.
Trimethylglycine is a safe and well tolerated nutrient that leads
to a significant biochemical and histological improvement in patients with nonalcoholic
steatohepatitis (NASH).
Trimethylglycine may lead to
sexual enhancement and enjoyment.
One capsule a day is usually sufficient for most people
to provide enhanced energy.
Other supplements used for mental enhancement include Mind Power Rx and
Alpha-GPC.
You can increase energy with an excellent doctor-formulated
multivitamin product.
For a supplement similar to TMG, consider
DMG. You can buy
DMG here. See also
Betaine hcl supplement
The Chemistry of DMG and
Trimethylglycine
DMG (dimethylglycine) is basically the amino acid glycine attached
to two methyl groups while TMG has three methyl groups.
In brief, choline (tetramethylglycine) has four methyl groups, and when it
donates a methyl group it becomes
Trimethylglycine
and when
Trimethylglycine
donates a methyl group it becomes DMG.
DMG, in turn, has two methyl groups left to methylate other substances in the body.
Commonly these methyl groups are added to homocysteine, converting it into the amino acid
methionine which is then converted to SAMe. SAMe is a nutrient available over the counter,
which has been used as a powerful antidepressant. DMG plays a crucial role in the respiratory cycle of the cells, transporting oxygen and
serving as a potent methyl donor. DMG acts as a building block for the synthesis of many
important substances such as choline, SAM-e, the amino acid methionine, several hormones,
neurotransmitters, and DNA. The formation of the neurotransmitters norepinephrine and
dopamine requires a methyl group donated by SAMe. Dopamine enhances sex drive.
TMG (trimethylglycine), also known as betaine,
is basically the amino acid glycine attached to three methyl groups. Simply,
Trimethylglycine
has one
more methyl group than DMG.
Trimethylglycine
emails
Q. I was reading your article on
Trimethylglycine
TMG. My husband (81) has a homocysteine of 14-16. He has
chronic kidney insufficiency. He also takes 2000 mcg of B-12 (for B-12
deficiency) and one B-100 a day, also 1000 mcg of folic acid (multivitamin +
B-100). In his condition, is it safe for him to try
Trimethylglycine TMG?
His doctor doesn't know anything about
Trimethylglycine
TMG and said his elevated homocysteine is from the kidney
disease.
A.
Trimethylglycine is a very potent nutrient that can cause
overstimulation, increased heart beat and insomnia. Those who are on high
dosages of other vitamins should be cautious in using Trimethylglycine due to
overstimulation, and if deciding to use it, should only take a small portion of
a pill. We suggest your doctor read more about Trimethylglycine to make the
recommendation since we only provide general information and we don't advise
whether to take or not take a supplement.