Vitamin B Complex and Coenzymes - Vitamin B deficiency
Vitamin b complex, vitamin b deficiency

A B vitamin supplement is the cheapest, safest, and most reliable way to improve your wellbeing and overall mental abilities. I recommend the Bs to those who wish to improve their mood, mental clarity, and energy. The effects of the B vitamins are subtle, especially in the young who normally have adequate dietary intake of these nutrients. Improvements in cognitive functions from the B vitamins are particularly noticeable in middle age individuals and the elderly. You can find vitamin B complex in an excellent doctor-formulated multivitamin product. For mental enhancement, see Mind Power Rx.

Vitamin B 1 --  Thiamin  Cocarboxylase, see also sulbutiamine and consider benfotiamine
Vitamin B 2 --  Riboflavin  Flavin Mono Nucleotide
Vitamin B 3 --  Niacin,  Nicotinamide NADH
Vitamin B 5 --  Pantothenic acid, Pantothene
Vitamin B 6 --  Pyridoxine Pyridoxal Phosphate

In order for the various vitamin B compounds to be utilized by the body, they must first be converted into their active coenzyme forms. This sublingual Coenzyme vitamin B Complex goes directly into your bloodstream in its active form, ready to go to work immediately.

Buy Vitamin B Coenzyme at Physician Formulas

Vitamin B Supplement Facts:
Vitamin C (as niacinamide ascorbate)
Thiamin (from 20 mg cocarboxylase [Coenzymated]) or you can purchase Benfotiamine
Riboflavin (from 15 mg flavin mononucleotide [Coenzymated™])
Niacin (from inositol 34 mg, niacinamide ascorbate 30 mg, nicotinamide adenine dinucleotide 10 mg [Coenzymated])
Vitamin B-6 (from 15 mg pyridoxal -5-phosphate [Coenzymated])
Folate (as folic acid)
Vitamin-B12 (from 1 mg dibencozide [Coenzymated])
Biotin vitamin B
Pantothenic Acid (as calcium D-Pantothenate) you can buy Pantothenic acid here.
Coenzyme Q10 (ubiquinone)
Inositol (as inositol hexanicotinate)

Vitamin B12 -- Cyanocobalamin  Dibencozide or Methylcobalamin
It is well established that the clinical manifestations of overt, severe vitamin B-12 deficiency include both hematologic (macrocytic or megaloblastic anemia) and neurologic (subacute combined degeneration of the spinal cord, peripheral neuropathy, cognitive impairment) sequelae. The neurologic consequences are of particular concern, because they can occur in the absence of hematologic symptoms and can become permanent if vitamin B-12 replacement therapy is not initiated within a year of the onset of symptoms. It therefore is incumbent on clinicians to recognize vitamin B-12 deficiency at an early stage, before the neurologic health of a person is irreversibly affected.
   The most common screening test for vitamin B12 deficiency is the measurement of total plasma or serum vitamin B-12. A total vitamin B-12 concentration <200 pg/mL is commonly considered indicative of vitamin B-12 deficiency. Total vitamin B-12 may not be the best screening measure for vitamin B-12 status, at least with respect to cognitive function in the elderly. Alternatives to total vitamin B-12 in screening for vitamin B-12 deficiency include holotranscobalamin (holoTC; the amount of total vitamin B-12 in serum bound to the transport protein transcobalamin) and methylmalonic acid and homocysteine, 2 metabolites that become elevated in the blood in vitamin B-12 deficiency. Of these 3, homocysteine has received the most attention and has been associated in many studies with poor cognitive function and increased risk of dementia. Elevated homocysteine is not specific to vitamin B-12 deficiency, however. It becomes elevated in various conditions, including folate and vitamin B-6 deficiencies, renal insufficiency, and hypothyroidism. Thus, homocysteine is not a particularly useful indicator of vitamin B-12 status in and of itself. Methylmalonic acid better reflects vitamin B-12 status and is a better predictor of cognitive function in older adults than is total vitamin B-12 or holoTC.

Vitamin B 1 deficiency
Vitamin B 1 deficiency or beriberi is a shortage of thiamine pyrophosphate, the active form of thiamine or vitamin B-1. A person can become deficient in vitamin B 1 either by not getting enough vitamin B-1 through the diet or by excess use. Excess use of vitamin B1 may occur in hyperthyroidism, pregnancy, lactation, or fever. Symptoms of vitamin B 1 deficiency include weakness and peripheral neuropathy.

Vitamin B 2 deficiency
Vitamin B 2 deficiency is almost always accompanied by deficiency of other vitamins. A deficiency of vitamin B 2 can be due to not getting enough of the vitamin from food, due to malabsorption in the intestine, the body not being able to use the vitamin, or an increase in the excretion of the vitamin from the body.

Vitamin B 3 deficiency
Severe deficiency of vitamin B3 causes pellagra, whereas mild deficiency slows down the metabolism, causing decreased tolerance to cold.

Vitamin B5 information
Q. I am slightly concerned about the possibility that vitamin B5 causes liver damage. I have read a couple of anecdotal stories of liver function abnormalities associated with vitamin B5 as well as an old study by Dr. Wirtschafter "Hepatocellular Lipid Changes Produced by Pantothenic Acid Excess." I was wondering whether you have come across any contrary studies or whether you believe that the study is of limited value because of flaws in the study or the limitations inherent in rat studies. Do you believe that vitamin B5 can raise the production of hydrochloric acid in the stomach to unacceptable levels?
   A. We know people who have taken 250 mg of vitamin B5 for decades without any apparent problems. However, as with almost any supplement or herb, it is a good idea to take a day off a week, a week off once a month or once every two months. It is also a good idea to not megadose on vitamins. We have not come across direct studies regarding the influence of vitamin B5 on hydrochloric acid.

Vitamin B 6 deficiency and information
Some of the symptoms of vitamin B 6 deficiency are Pellagra-like symptoms, lowered immunity, and anemia.

Q. Can one over-dose on vitamin B6 for instance, taking 50 mg. twice a day. What side effects might be expected with the vitamin B-6
   A. Vitamin B6 may cause nerve damage in doses usually over 200 mg but some people may be more susceptible to lower dosages causing harm. Plus, it may disturb delicate biochemical balance with other B vitamins in the body in some people.

Vitamin B 12 deficiency
Vitamin B12 deficiency is a common cause of macrocytic anemia.

Vitamin B questions
Q. I'm considering taking a sublingual B-12 vitamin. I have a thyroid disorder (Hashimoto's thyroidits) but I'm not currently taking any thyroid medicine. I've been feeling a little fatigued, irritable and don’t' feel 100%. I also have some issues of feeling "off balance" when walking that I haven't been able to resolve after numerous blood tests. I was wondering if you could recommend a good brand for this? Also, I noticed that only 1 brand (TriVita) includes B6 and Foilc Acid in their B-12 product. Is it essential to have all three of these combined? Any help you could provide would be appreciated.
   A. As a general rule we suggest using a multivitamin that has all the vitamin B complex rather than just one vitamin B.

Q. Folic acid vitamin b email - We think not all people can fully metabolize folic acid. The synthetic folate supplement attempts to replicate natural dietary folate and is eventually broken down into L-methylfolate by many; but not all patients. In particular, several studies note that as many as half the general population get only a partial benefit from FA and as many as 10-12% get virtually no benefit from folic acid. The MTHFR polymorphism is a clear cause of this inefficiency with synthetic FA as the synthetic FA is never metabolized into l-methylfolate to become useful at the cellular level. Merck, kGa (Germany) has recently developed L-methylfolate in an oral dose form. We are using it now in several of the products that our company manufacturers and markets. In particular, we are using it in a prenatal care product branded as NEEVO which is now specifically indicated for use in patients with MTHFR, high-risk pregnancies and for advanced maternal age. Further, L-methylfolate is: 7 times more bioavailable than FA (Willems, 2004) · Better at reducing the risk of NTD than FA (Lamers, 2006) · Better at increasing RBC folate than FA (Lamers, 2006). We would be happy to share some of the clinical data with you. Sincerely, NEEVO Product Manager.
   A. We will await more research studies to determine whether L-methylfolate offers any advantages over folic acid supplements.

Additional links
Saw Palmetto extract 160 mg is often found with pygeum bark
Sitosterol extract also known as beta sitosterol
Supplements and Herbal Index tongkat ali home page