Zestra information
Zestra is marketed as a sexual enhancement for woman product. One study shows it has positive benefits. A Medline search in April 2009 did not reveal any further studies with this formula since 2003.
Zestra study
Randomized, placebo-controlled, double blind, crossover
design trial of the efficacy and safety of Zestra for Women in women with and
without female sexual arousal disorder.
J Sex Marital Ther. 2003;29 Suppl 1:33-44. Ferguson DM, et al. Clinical
Development Services, Grand Marais, Minnesota, USA
Zestra for Women is a botanical feminine massage oil formulated to enhance
female sexual pleasure and arousal when applied to the vulva. We conducted this
randomized, double-blinded, crossover study to evaluate the efficacy and safety
of Zestra for Women compared to placebo oil in 10 women with and 10 women
without female sexual arousal disorder (FSAD) in conditions of home use in
conjunction with sexual activities. Subjects were screened by physical
examination, sex therapist interviews, and questionnaires. We randomized
qualified subjects to treatment paths and gave them 5 doses of test article and
diaries to use at home. At Visit 2, we assessed them by questionnaires and gave
them 5 doses of crossover test article and diaries to use at home. At the final
visit, we assessed them with questionnaires. We assessed safety by adverse event
reports and primary efficacy by responses to a diary question regarding
satisfaction with arousal. Secondary efficacy instruments included remaining
diary questions, recall-based questionnaires, global assessment questions, and a
consumer-testing questionnaire. All 20 subjects completed the study. Three
subjects reported single incidences of mild genital burning sensations lasting
5-30 min after use of Zestra for Women. Both normal and FSAD women showed
statistically significant improvements, relative to placebo, in level of
arousal, level of desire, satisfaction with arousal, genital sensation, ability
to have orgasms, and sexual pleasure. Although FSAD women showed greater
magnitude of response, the presence of FSAD had no effect on response rates.
Zestra for Women was just as effective in women using selective serotonin
reuptake inhibitor antidepressants as in women not using antidepressants. Zestra
for Women improved sexual function in normal and FSAD women under conditions of
home use.
Zestra Questions
Q. Does Zestra work for libido?
A. We have not tested Zestra ourselves so we don't know. There
appears to be one study with Zestra thus far that showed good results.
For more information on sexual health research updates and female libido improvement.